CD58

CD58

protein
Name=CD58 molecule
caption=


width=
HGNCid=1688
Symbol=CD58
AltSymbols=LFA3
EntrezGene=965
OMIM=153420
RefSeq=NM_001779
UniProt=P19256
PDB=
ECnumber=
Chromosome=1
Arm=p
Band=13
LocusSupplementaryData=

CD58, or lymphocyte function-associated antigen 3 (LFA-3), is a cell adhesion molecule.cite journal | author = Barbosa JA, Mentzer SJ, Kamarck ME, Hart J, Biro PA, Strominger JL, Burakoff SJ | title = Gene mapping and somatic cell hybrid analysis of the role of human lymphocyte function-associated antigen-3 (LFA-3) in CTL-target cell interactions | journal = J. Immunol. | volume = 136 | issue = 8 | pages = 3085–91 | year = 1986 | month = April | pmid = 3514752 | url = http://www.jimmunol.org/cgi/pmidlookup?view=long&pmid=3514752 | issn = ] cite journal | author = Wallich R, Brenner C, Brand Y, Roux M, Reister M, Meuer S | title = Gene structure, promoter characterization, and basis for alternative mRNA splicing of the human CD58 gene | journal = J. Immunol. | volume = 160 | issue = 6 | pages = 2862–71 | year = 1998 | month = March | pmid = 9510189 | url = http://www.jimmunol.org/cgi/content/abstract/160/6/2862 | issn = ]

It binds to CD2.cite journal | author = Wang JH, Smolyar A, Tan K, Liu JH, Kim M, Sun ZY, Wagner G, Reinherz EL | title = Structure of a heterophilic adhesion complex between the human CD2 and CD58 (LFA-3) counterreceptors | journal = Cell | volume = 97 | issue = 6 | pages = 791–803 | year = 1999 | month = June | pmid = 10380930 | doi = 10.1016/S0092-8674(00)80790-4 | url = | issn = ]

References

External links

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