Shaking rat Kawasaki

Shaking rat Kawasaki

Shaking rat Kawasaki (SRK) is an autosomal recessive mutant rat that has a short deletion in the reelin gene. Kikkawa S, Yamamoto T, Misaki K, Ikeda Y, Okado H, Ogawa M, Woodhams PL, Terashima T. (2003) "Missplicing resulting from a short deletion in the reelin gene causes reeler-like neuronal disorders in the mutant shaking rat Kawasaki." J Comp Neurol. 2003 Aug 25;463(3):303-15. PMID 12820163 ] This results in the lowered expression of reelin protein and reeler-like phenotype. Shaking rat Kawasaki was first described in 1988. Aikawa H, Nonaka I, Woo M, Tsugane T, Esaki K. (1988) "Shaking rat Kawasaki (SRK): a new neurological mutant rat in the Wistar strain." Acta Neuropathol (Berl). 1988;76(4):366-72. PMID 3176902 [http://www.springerlink.com/content/h6058tv06866hu51/fulltext.pdf free fulltext] ]

See also

* Reelin
* Reeler

References


Wikimedia Foundation. 2010.

Игры ⚽ Нужен реферат?

Look at other dictionaries:

  • Дрожащая крыса Кавасаки — Значимость предмета статьи поставлена под сомнение. Пожалуйста, покажите в статье значимость её предмета, добавив в неё доказательства значимости по частным критериям значимости или, в случае если частные критерии значимости для… …   Википедия

  • Molecular neuroscience — is a branch of neuroscience that examines the biology of the nervous system with molecular biology, molecular genetics, protein chemistry and related methodologies.[1] Molecular biology studies how deoxyribonucleic acid (DNA) forms ribonucleic… …   Wikipedia

  • Reeler — The reeler is an autosomal recessive mouse mutant, in which cortical neurons are generated normally but are abnormally placed, resulting in disorganization of cortical laminar layers in the CNS. The reason is the lack of Reelin, an extracellular… …   Wikipedia

Share the article and excerpts

Direct link
… Do a right-click on the link above
and select “Copy Link”