Filippo Pacini


Filippo Pacini

Infobox Scientist
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name = Filippo Pacini


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birth_date = 1812-05-25
birth_place = Pistoia, Tuscany
death_date = 1883-07-09
death_place = Florence
residence = Florence
citizenship = Italian
nationality = Italian
ethnicity = Italian
fields = Anatomy
workplaces = Institute of Human Anatomy
Florence Lyceum
University of Florence Istituto di Studi Superiori
alma_mater = Pistoia
doctoral_advisor = Paolo Savi
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known_for = Pacinian corpuscles
Vibrio cholerae
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religion = Roman Catholic


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Filippo Pacini (May 25, 1812July 9, 1883) was an Italian anatomist, posthumously famous for isolating the cholera bacillus "Vibrio cholerae" in 1854, well before Robert Koch's more widely accepted discoveries thirty years later.

Pacini was born in Pistoia, Tuscany to a humble family, but was given a religious education in hopes that he would become a bishop. However, in 1830 he was given a scholarship to the venerable medical school in Pistoia. He learned his trade as a physician, and learned to dissect and examine bodies with a microscope.

In 1831, during a dissection class, Pacini discovered small sensory organs in the nervous system which can detect pressure and vibrations. He studied them closely from 1833 on, and first discussed them in 1835 at the "Società medico-fisica" in Florence, but did not publish his research ("Nuovi organi scoperti nel corpo umano") until 1840. Within just a few years, the work was widely known in Europe and the bodies had become known as Pacinian corpuscles.

He served as an assistant to Paolo Savi in Pisa from 1840 to 1843, then began working at the Institute of Human Anatomy. In 1847 Pacini began teaching at the Lyceum in Florence, and then was named chair of General and Topographic Anatomy at the "Istituto di Studi Superiori" at the University of Florence in 1849, where he remained to the end of his career.

The Asiatic Cholera Pandemic of 1846-63 which swept through Florence in 1845–1846 brought the disease to the center of Pacini's attention. In 1854 he described the disease in a paper called "Microscopical observations and pathological deductions on cholera", but because of the prevailing belief of Italian scientists in the miasma theory of disease, the work was not noted by others until many years after his death, despite additional publications in 1865, 1866, 1871, 1876, and 1880 which identified the cause of the disease's lethality, and even proposed some effective treatments. John Snow, who disproved the miasma theory, and Robert Koch, widely credited with the discovery of the bacillum thirty years later, were unaware of his previous work.

When Koch, a much more widely respected scientist who had previously identified the tuberculosis bacillus, presented his findings to the Cholera Commission of the Imperial Health Office in Berlin in 1884, the commission congratulated him, but also recognized Pacini's previous discovery of the bacterium. In 1965, the international committee on nomenclature adopted the formal name "Vibrio cholerae Pacini 1854" to honor his work.

During his career Pacini also published several studies on the retina of the human eye, the electric organs in electric fishes, the structure of bone, and the mechanics of respiration.

Pacini did not marry, and spent most of the money remaining after his scientific investigation on the long term care of his two ailing sisters. He died nearly penniless in Florence on July 9, 1883, and was buried in the cemetery of the Misericordia. In 1935 his remains were transferred to the church of Santa Maria delle Grazie, along with the remains Atto Tigri and Filippo Civinini, two other noted anatomists.

References

* [http://www.ph.ucla.edu/epi/snow/firstdiscoveredcholera.html UCLA: Who first discovered cholera?]
* [http://www.whonamedit.com/doctor.cfm/2605.html Who Named It: Filippo Pacini]


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Look at other dictionaries:

  • Filippo Pacini — (1870) Filippo Pacini (25 mai 1812–9 juillet 1883) était un anatomiste italien, devenu célèbre après sa mort pour avoir isolé le bacille du choléra (Vibrio cholerae) en 1854, une trentaine d années avant que Robert Koch ne refît cette découverte… …   Wikipédia en Français

  • Filippo Pacini — Saltar a navegación, búsqueda Filippo Pacini Filipo Pacini …   Wikipedia Español

  • Filippo Pacini — 1870 Filippo Pacini (* 25. Mai 1812 in Pistoia; † 9. Juli 1883 in Florenz) war ein italienischer Anatom. Pacini stammte aus einer ärmlichen Familie und sollte zunächst Theologe werden. 1830 erhielt er jedoch ein Stipendium an der angesehenen… …   Deutsch Wikipedia

  • Filippo Pacini — n. (1812 1883) Italian anatomist who discovered Vibrio cholerae in 1854 …   English contemporary dictionary

  • corpuscule de Pacini (du nom de l'anatomiste italien Filippo Pacini [1812-1883]) — ● corpuscule de Pacini (du nom de l anatomiste italien Filippo Pacini [1812 1883]) Terminaison sensorielle tactile encapsulée, qu on trouve au niveau de la peau, des articulations et des viscères …   Encyclopédie Universelle

  • Pacini — ist der Name folgender Personen: Alfredo Pacini (1888–1967), vatikanischer Diplomat Filippo Pacini (1812–1883), italienischer Anatom Giovanni Pacini (1796–1867), italienischer Opernkomponist Piero Pacini (* um 1440; † um 1513), italienischer… …   Deutsch Wikipedia

  • Pacini — may refer to:* Filippo Pacini, an Italian anatomist. * Roberto Pacini, an Italian director, author and theatre and film producer. * Alfredo Pacini, an Italian prelate of the Roman Catholic Church. * Giovanni Pacini, an Italian composer.* Pacinian …   Wikipedia

  • Filippo — ist die italienische Variante des männlichen Vornamens Philipp. Bekannte Namensträger Vorname (Auswahl) Filippo Brunelleschi (1377–1446), italienischer Architekt und Bildhauer der Frührenaissance Filippo Inzaghi (* 1973), italienischer… …   Deutsch Wikipedia

  • Pacini — El término Pacini en Wikipedia hace referencia a: Pietro Pacini, editor italiano del siglo XVI; Salvatore Pacini, obispo italiano (1506 ?); Giovanni Pacini, arquitecto italiano, (1778–1838); Giovanni Pacini, compositor italiano (1796 1867);… …   Wikipedia Español

  • Pacini-Korpuskel — Anatomische Zeichnung Vater Pacini Körperchen sind rasch adaptierende Mechanorezeptoren der Haut, die besonders gut Vibrationsempfindungen vermitteln. Sie sind benannt nach dem deutschen Anatomen Abraham Vater (1684–1751) und dem italienischen… …   Deutsch Wikipedia


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