ANGPT2


ANGPT2

Angiopoietin 2, also known as ANGPT2, is a human gene.

PBB_Summary
section_title =
summary_text = Naturally occurring antagonist for both ANGPT1 and TIE2; expressed only at the sites of vascular remodeling; similar to angiopoietin-1 [cite web | title = Entrez Gene: ANGPT2 angiopoietin 2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=285| accessdate = ]

ee also

* Angiopoietin

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Maruyama K, Sugano S |title=Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. |journal=Gene |volume=138 |issue= 1-2 |pages= 171–4 |year= 1994 |pmid= 8125298 |doi=
*cite journal | author=Maisonpierre PC, Suri C, Jones PF, "et al." |title=Angiopoietin-2, a natural antagonist for Tie2 that disrupts in vivo angiogenesis. |journal=Science |volume=277 |issue= 5322 |pages= 55–60 |year= 1997 |pmid= 9204896 |doi=
*cite journal | author=Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, "et al." |title=Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library. |journal=Gene |volume=200 |issue= 1-2 |pages= 149–56 |year= 1997 |pmid= 9373149 |doi=
*cite journal | author=Cheung AH, Stewart RJ, Marsden PA |title=Endothelial Tie2/Tek ligands angiopoietin-1 (ANGPT1) and angiopoietin-2 (ANGPT2): regional localization of the human genes to 8q22.3-q23 and 8p23. |journal=Genomics |volume=48 |issue= 3 |pages= 389–91 |year= 1998 |pmid= 9545648 |doi= 10.1006/geno.1997.5207
*cite journal | author=Sato A, Iwama A, Takakura N, "et al." |title=Characterization of TEK receptor tyrosine kinase and its ligands, Angiopoietins, in human hematopoietic progenitor cells. |journal=Int. Immunol. |volume=10 |issue= 8 |pages= 1217–27 |year= 1998 |pmid= 9723709 |doi=
*cite journal | author=Tanaka S, Mori M, Sakamoto Y, "et al." |title=Biologic significance of angiopoietin-2 expression in human hepatocellular carcinoma. |journal=J. Clin. Invest. |volume=103 |issue= 3 |pages= 341–5 |year= 1999 |pmid= 9927494 |doi=
*cite journal | author=Valenzuela DM, Griffiths JA, Rojas J, "et al." |title=Angiopoietins 3 and 4: diverging gene counterparts in mice and humans. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=96 |issue= 5 |pages= 1904–9 |year= 1999 |pmid= 10051567 |doi=
*cite journal | author=Grosios K, Leek JP, Markham AF, "et al." |title=Assignment of ANGPT4, ANGPT1, and ANGPT2 encoding angiopoietins 4, 1 and 2 to human chromosome bands 20p13, 8q22.3-->q23 and 8p23.1, respectively, by in situ hybridization and radiation hybrid mapping. |journal=Cytogenet. Cell Genet. |volume=84 |issue= 1-2 |pages= 118–20 |year= 1999 |pmid= 10343124 |doi=
*cite journal | author=Procopio WN, Pelavin PI, Lee WM, Yeilding NM |title=Angiopoietin-1 and -2 coiled coil domains mediate distinct homo-oligomerization patterns, but fibrinogen-like domains mediate ligand activity. |journal=J. Biol. Chem. |volume=274 |issue= 42 |pages= 30196–201 |year= 1999 |pmid= 10514510 |doi=
*cite journal | author=Kim I, Kim JH, Ryu YS, "et al." |title=Characterization and expression of a novel alternatively spliced human angiopoietin-2. |journal=J. Biol. Chem. |volume=275 |issue= 24 |pages= 18550–6 |year= 2000 |pmid= 10766762 |doi= 10.1074/jbc.M910084199
*cite journal | author=Mezquita J, Mezquita P, Montserrat P, "et al." |title=Genomic structure and alternative splicing of chicken angiopoietin-2. |journal=Biochem. Biophys. Res. Commun. |volume=275 |issue= 2 |pages= 643–51 |year= 2000 |pmid= 10964717 |doi= 10.1006/bbrc.2000.3345
*cite journal | author=Xu Y, Yu Q |title=Angiopoietin-1, unlike angiopoietin-2, is incorporated into the extracellular matrix via its linker peptide region. |journal=J. Biol. Chem. |volume=276 |issue= 37 |pages= 34990–8 |year= 2001 |pmid= 11447223 |doi= 10.1074/jbc.M103661200
*cite journal | author=Acker T, Beck H, Plate KH |title=Cell type specific expression of vascular endothelial growth factor and angiopoietin-1 and -2 suggests an important role of astrocytes in cerebellar vascularization. |journal=Mech. Dev. |volume=108 |issue= 1-2 |pages= 45–57 |year= 2002 |pmid= 11578860 |doi=
*cite journal | author=Ward EG, Grosios K, Markham AF, Jones PF |title=Genomic structures of the human angiopoietins show polymorphism in angiopoietin-2. |journal=Cytogenet. Cell Genet. |volume=94 |issue= 3-4 |pages= 147–54 |year= 2002 |pmid= 11856872 |doi=
*cite journal | author=Huang YQ, Li JJ, Hu L, "et al." |title=Thrombin induces increased expression and secretion of angiopoietin-2 from human umbilical vein endothelial cells. |journal=Blood |volume=99 |issue= 5 |pages= 1646–50 |year= 2002 |pmid= 11861279 |doi=
*cite journal | author=Hata K, Udagawa J, Fujiwaki R, "et al." |title=Expression of angiopoietin-1, angiopoietin-2, and Tie2 genes in normal ovary with corpus luteum and in ovarian cancer. |journal=Oncology |volume=62 |issue= 4 |pages= 340–8 |year= 2002 |pmid= 12138242 |doi=
*cite journal | author=Lin S, Shyu KG, Lee CC, "et al." |title=Hyperbaric oxygen selectively induces angiopoietin-2 in human umbilical vein endothelial cells. |journal=Biochem. Biophys. Res. Commun. |volume=296 |issue= 3 |pages= 710–5 |year= 2002 |pmid= 12176040 |doi=
*cite journal | author=Geva E, Ginzinger DG, Zaloudek CJ, "et al." |title=Human placental vascular development: vasculogenic and angiogenic (branching and nonbranching) transformation is regulated by vascular endothelial growth factor-A, angiopoietin-1, and angiopoietin-2. |journal=J. Clin. Endocrinol. Metab. |volume=87 |issue= 9 |pages= 4213–24 |year= 2002 |pmid= 12213874 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Paradis V, Bièche I, Dargère D, "et al." |title=A quantitative gene expression study suggests a role for angiopoietins in focal nodular hyperplasia. |journal=Gastroenterology |volume=124 |issue= 3 |pages= 651–9 |year= 2003 |pmid= 12612904 |doi= 10.1053/gast.2003.50104

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