- Generalized lymphadenopathy
Lymph nodes or 'glands' or "nodes" or "lymphoid tissue".are nodular bodies located throughout the body but clustering in certain areas such as the armpit, back of the neck and the groin. They are part of the lymphatic system.
lymphatic systemis part of the body's immune surveillance system. Bloodcontains fluidand blood cells. The fluid, which may contain suspended foreign material such as bacteriaand viruses, seeps through blood vesselwalls into the tissues, where it bathes the body cells and exchanges substances with them. Some of this fluid is then taken up by lymphatic vessels and passed back to the heart, where it is again mixed with the blood. On its way the fluid passes through the lymph nodes. If nodes detect something foreign passing through them such as a bacterium or a cancer cell they will swell up. This is called " lymphadenopathy" or "swollen glands". Usually this is localised (for example an infected spot on the scalpwill cause lymph nodes in the neck on that same side to swell up), but when it is all over the body it is called "generalized lymphadenopathy".
Usually this is in response to a body-wide infectious disease such as
influenzaand will go away once the person has recovered, but sometimes it can persist long-term, even when there is no obvious cause of disease. This is then called " persistent generalized lymphadenopathy" (PGL).
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