CXCL17

protein
Name = chemokine (C-X-C motif) ligand 7
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HGNCid =
Symbol = CXCL17
AltSymbols = SCYB17, VCC-1, DMC
EntrezGene = 284340
OMIM =
RefSeq = NM_198477
UniProt = Q6UXB2
PDB =
ECnumber =
Chromosome = 19
Arm = q
Band = 13.2
LocusSupplementaryData =

Chemokine (C-X-C motif) ligand 17 (CXCL17) is a small cytokine belonging to the CXC chemokine family that has been identified in humans and mice. CXCL17 attracts dendritic cells and monocytes and is regulated in tumors. It is also known as "VEGF co-regulated chemokine 1 (VCC-1)" and "dendritic cell- and monocyte-attracting chemokine-like protein" (DMC). [cite journal |author=Weinstein E, Head R, Griggs D, Sun D, Evans R, Swearingen M, Westlin M, Mazzarella R |title=VCC-1, a novel chemokine, promotes tumor growth |journal=Biochem Biophys Res Commun |volume=350 |issue=1 |pages=74–81 |year=2006 |pmid=16989774 |doi=10.1016/j.bbrc.2006.08.194] cite journal |author=Pisabarro M, Leung B, Kwong M, Corpuz R, Frantz G, Chiang N, Vandlen R, Diehl L, Skelton N, Kim H, Eaton D, Schmidt K |title=Cutting edge: novel human dendritic cell- and monocyte-attracting chemokine-like protein identified by fold recognition methods |journal=J Immunol |volume=176 |issue=4 |pages=2069–73 |year=2006 |pmid=16455961] This chemokine is constitutively expressed in the lung. The gene for human CXCL17 is located on chromosome 19.

References