Drug Discovery Today

Drug Discovery Today

Drug Discovery Today (ISSN 1359-6446) is a monthly review journal that is published by Elsevier and was launched in 1996. The journal publishes 24 issues per year as 12 monthly double issues, and covers the whole of the preclinical drug discovery process from target identification and validation through hit identification, lead identification and optimisation to candidate selection. The journal serves as a source of information for drug researchers, both in industry and academia.

Each issue of the journal contains a short front section and review articles. The front section contains an Editorial (opinion articles intended to engender debate around a topic) and a Perspective article, which might be an Interview with a leading figure in drug discovery or a Biotech Focus that highlights the biotechnology activities in a particular geographic location. Occasionally, Business Trends articles are included, in which experts review trends in the approaches to treat disease classes. In the review section, Keynote Reviews and Foundation Reviews provide broad, authoritative coverage of a particular topic.

The Short Reviews deal with focused topics and are categorised as: Gene To Screen, which deals with the earliest part of drug discovery and all aspects involved in target identification, validation and assay development; Informatics, which deals with all aspects of computational biology and chemistry related to drug discovery; and Post Screen, which covers the science from hit identification to candidate selection, clinical trial design and patent issues. The short Monitor section highlights recent developments in medicinal chemistry, and the Diary section points readers to the most appropriate future conferences in drug discovery.

Topics covered include:

  • Genomics and proteomics
  • Target identification and validation
  • Assay development
  • Library design
  • Computational chemistry and biology
  • Medicinal chemistry
  • Novel therapeutic strategies
  • Drug delivery
  • Formulation
  • Biotherapeutics
  • ADME–Tox
  • Business strategy
  • Clinical trials

In 2004, the Drug Discovery Today journal series expanded with the launch of four online-only review journals: Drug Discovery Today: Disease Mechanisms, Drug Discovery Today: Disease Models, Drug Discovery Today: Therapeutic Strategies and Drug Discovery Today: Technologies. The four journals systematically cover the essential developments across the breadth of therapeutic areas and technologies relevant to the drug discovery and development pipeline.

See also

  • Trends in Pharmacological Sciences (review journal)

External links

  • Drug Discovery Today on Elsevier.com *[1]
  • Drug Discovery Today website [2]
  • Drug Discovery Today online [3]

Wikimedia Foundation. 2010.

Игры ⚽ Нужен реферат?

Look at other dictionaries:

  • Drug Discovery Today —   Titre abrégé Drug Discov. Today Discipline Pharmacologie Langue Anglais Directeur de p …   Wikipédia en Français

  • Drug discovery — In the fields of medicine, biotechnology and pharmacology, drug discovery is the process by which drugs are discovered and/or designed. In the past most drugs have been discovered either by identifying the active ingredient from traditional… …   Wikipedia

  • Nature Reviews Drug Discovery —   Titre abrégé Nat. Rev. Drug Discov. Discipline Pharmacologie, microbiologie Langue Anglais …   Wikipédia en Français

  • Discovery and development of nucleoside and nucleotide reverse-transcriptase inhibitors — (NRTIs and NtRTIs) began in the 1980s when the AIDS epidemic hit Western societies. NRTIs inhibit the reverse transcriptase (RT), an enzyme that controls the replication of the genetic material of the human immunodeficiency virus (HIV). The first …   Wikipedia

  • Natural product drug discovery — This article describes the utilization of natural resources in the process of finding new drug compounds, an approach commonly referred to as natural product drug discovery . Together with synthetic chemistry, they represent complementary… …   Wikipedia

  • Collaborative Drug Discovery — Collaborative Drug Discovery, Inc. Type Private Industry Life Sciences, Informatics Founded 2004 Headquarters Burlingame, California Products …   Wikipedia

  • Drug Resistance Updates —   Titre abrégé Drug Resist. Update Discipline Pharmacologie Langue Anglais Direct …   Wikipédia en Français

  • Discovery and development of TRPV1 antagonists — Chronic pain remains a recognized unmet medical need. Consequently, the search for new analgesic agents is being intensively studied by the pharmaceutical industry. The TRPV1 receptor is an ion channel that has been implicated in mediation of… …   Wikipedia

  • Discovery and development of antiandrogens — In the 1960s, the first antiandrogen, or androgen antagonist, was discovered. Antiandrogens antagonise the androgen receptor (AR) and thereby block the biological effects of testosterone and dihydrotestosterone (DHT). Antiandrogens are important… …   Wikipedia

  • Discovery and development of dual serotonin and norepinephrine reuptake inhibitors — Serotonin–norepinephrine reuptake inhibitors (SNRIs) are a class of antidepressant drugs used in the treatment of major depressive disorder (MDD). SNRIs are potent inhibitors of serotonin (5 Hydroxytryptamine, 5 HT) and norepinephrine (NE,… …   Wikipedia

Share the article and excerpts

Direct link
… Do a right-click on the link above
and select “Copy Link”