Wandering spleen


Wandering spleen

Infobox_Disease
Name = PAGENAME


Caption = A picture of an enlarged spleen taken using medical ultrasonography.
DiseasesDB = 33272
ICD10 =
ICD9 = ICD9|289.59
ICDO =
OMIM =
MedlinePlus =
eMedicineSubj =
eMedicineTopic =
MeshID = D050805

Wandering spleen (or Pelvic spleen) is a rare medical disease caused by the loss or weakening of the ligaments that help to hold the spleen.

Background

Wandering spleen is most commonly diagnosed in young childrencite web | first=Malak | last=Hasan Alawi | coauthors=Ahmad Khalifa, Sami Hassan Bana | title=Wandering Spleen: A Challenging Diagnosis | format = PDF | publisher=Open Publishing | date=October-December 2005 | work=Pakistan Journal of Medical Sciences | url=http://www.pjms.com.pk/issues/octdec05/pdf/wandering_spleen.pdf| accessdate=2007-02-25 ] as well as women between the ages of 20 and 40.cite web | coauthors= Safioleas MC, Stamatakos MC, Diab AI, Safioleas PM | title=Wandering spleen with torsion of the pedicle | publisher=Saudi Med J.| date=January 28, 2007 | url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=17206307&query_hl=3&itool=pubmed_docsum| accessdate=2007-02-25 ] Even so, the disease is very rare and fewer than 500 occurrences of the disease have been reported as of 2005,cite web | first=Malak | last=Hasan Alawi | coauthors=Ahmad Khalifa, Sami Hassan Bana | title=Wandering Spleen: A Challenging Diagnosis | format = PDF | publisher=Open Publishing | date=October-December 2005 | work=Pakistan Journal of Medical Sciences | url=http://www.pjms.com.pk/issues/octdec05/pdf/wandering_spleen.pdf| accessdate=2007-02-25 ] of which around 148 (including both children and adult cases) were documented to have been from between 1960 and 1992.cite web | coauthors=T. Satyadas, N. Nasir and H.A. Bradpiece | title=Wandering spleen: case report and literature review | publisher=University Department of Surgery, Royal Free Hospital and University Medical School, London, U.K. | date=April 27, 2002 | url=http://www.rcsed.ac.uk/journal/vol47_2/4720012.html| accessdate=2007-03-02 ] Less than 0.5% of all splenectomies, surgical removal of the spleen, are performed due to having this disorder.

Characteristics of the disorder include the loss, weakening, or malformation of the ligamentscite web | title=Wandering Spleen | publisher=NORD | url=http://www.rarediseases.org/search/rdbdetail_abstract.html?disname=Wandering%20Spleen| accessdate=2007-02-25 ] that help to keep the spleen located in the upper left part of the abdomen. Though not a genetic disease, wandering spleen is often found at birth. It can occur in adults as the result of injuries and other similar conditions that cause the ligaments to weaken, such as connective tissue disease or pregnancy.cite web | title=Wandering Spleen | publisher=NORD | url=http://www.rarediseases.org/search/rdbdetail_abstract.html?disname=Wandering%20Spleen| accessdate=2007-02-25 ]

ymptoms

Symptoms include an enlargement in the size of the spleen,cite web | title=Wandering Spleen | publisher=NORD | url=http://www.rarediseases.org/search/rdbdetail_abstract.html?disname=Wandering%20Spleen| accessdate=2007-02-25 ] or a change from the spleen's original position to another location, usually in either other parts of the abdomen or into the pelvis. This ability to move to other locations is commonly attributed to the spleen's pedicle being abnormally long.cite web | first=Malak | last=Hasan Alawi | coauthors=Ahmad Khalifa, Sami Hassan Bana | title=Wandering Spleen: A Challenging Diagnosis | format = PDF | publisher=Open Publishing | date=October-December 2005 | work=Pakistan Journal of Medical Sciences | url=http://www.pjms.com.pk/issues/octdec05/pdf/wandering_spleen.pdf| accessdate=2007-02-25 ]

Physical factors may cause ischuria, constipation, as well as numerous spleen-related diseases such as hypersplenism, thrombocytopenia, and lymphoma.cite web | coauthors=T. Satyadas, N. Nasir and H.A. Bradpiece | title=Wandering spleen: case report and literature review | publisher=University Department of Surgery, Royal Free Hospital and University Medical School, London, U.K. | date=April 27, 2002 | url=http://www.rcsed.ac.uk/journal/vol47_2/4720012.html| accessdate=2007-03-02 ] Blocking of the arteries and torsion in the spleen can also result in abdominal pain or swelling.cite web |url=http://www.medcyclopaedia.com/library/topics/volume_vii/w/wandering_spleen.aspx |title= Wandering spleen |accessdate=2007-02-26 |format= |work= ] However, lack of visible symptoms — except in incidents of abdominal pain — makes the disease difficult for doctors to diagnose,cite web | coauthors= Safioleas MC, Stamatakos MC, Diab AI, Safioleas PM | title=Wandering spleen with torsion of the pedicle | publisher=Saudi Med J.| date=January 28, 2007 | url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=17206307&query_hl=3&itool=pubmed_docsum| accessdate=2007-02-25 ] though medical imaging techniques such as medical ultrasonography, magnetic resonance imaging, or computed tomography can be used to confirm its occurrence.

Treatment

The disorder must be treated through laparoscopic surgery, due to the possibility of blocked arteries in the spleen. The usual treatment is splenopexy, fixation of the spleen, but if there is no blood flow after unwinding the spleen through detorsion then splenectomy must be performed.cite web | first=MC | last=Safioleas | coauthors= Stamatakos MC, Diab AI, Safioleas PM | title=Wandering spleen with torsion of the pedicle | publisher=Saudi Med J.| date=January 28, 2007 | url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=17206307&query_hl=3&itool=pubmed_docsum| accessdate=2007-02-25 ] Although there have been few reported cases of treatment through laparoscopic surgery due to the rarity of the disease, it has been proven to be an effective surgical technique.cite web | coauthors= Castellon-Pavon CJ, Valderrabano-Gonzalez S, Anchustegui-Melgarejo P, Alvarez-Alvarez J, Morales-Artero S, Perez-Algar C, Corrales-Castillo, Garcia-Serrano FR | title=Laparoscopic splenectomy due to torsion of a wandering spleen | publisher= Cir Esp.| date=December, 2006 | url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=17192227&query_hl=3&itool=pubmed_docsum| accessdate=2007-02-25 ]

Notes and references


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