Bombesin


Bombesin

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Section1= Chembox Identifiers
CASNo=31362-50-2
PubChem=16133891
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Section2= Chembox Properties
Formula=C71H110N24O18S
MolarMass=1619.85
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Section3= Chembox Hazards
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Bombesin is a 14 amino acid peptide originally isolated from the skin of a frog. It has two known homologs in mammals called neuromedin B and gastrin releasing peptide. It stimulates gastrin release from G cells. It activates three different G-protein coupled receptors known as BBR1 2 & 3. It also activates these receptors in the brain. Together with cholecystokinin it is the second major source of negative feedback signals that stop eating behaviour.

Bombesin is also a tumor marker for lung cancer, gastric cancer and neuroblastoma.

ee also

*Neuromedin B
*Neuromedin U


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Look at other dictionaries:

  • Bombesin — (Bombina bombina) Strukturformel …   Deutsch Wikipedia

  • bombesin — [bäm′bə sin] n. a short polypeptide in some animals, esp. in the brain and stomach of a mammal, that stimulates the activity of the nervous, endocrine, and immune systems * * * …   Universalium

  • bombesin — [bäm′bə sin] n. a short polypeptide in some animals, esp. in the brain and stomach of a mammal, that stimulates the activity of the nervous, endocrine, and immune systems …   English World dictionary

  • bombesin — Tetradecapeptide neurohormone with both paracrine and autocrine effects first isolated from skin of fire bellied toad ( Bombina bombina ) ; mammalian equivalent is gastrin releasing peptide (GRP). Bombesin cross reacts with GRP receptors. Both… …   Dictionary of molecular biology

  • bombesin — noun A neural oligopeptide that stimulates the release of gastrin …   Wiktionary

  • bombesin — Pharmacologically active tetradecapeptide found in skins of European amphibians of the family Discoglossidae, principally Bombina bombina and Bombina variegata variegata. A potent stimulant of gastric and pancreatic secretions; a bombesinlike… …   Medical dictionary

  • Bombesin — Bom|be|sin [nlat. Bombina = Unke (Zool.)], das; s, e: ein gastrointestinales, insbes. die Körpertemp. stark senkendes Hormon aus 14 Aminosäuren (↑ Kinin) …   Universal-Lexikon

  • Bombesin-like receptor 3 — The bombesin like receptor 3 (BRS 3) is a G protein coupled receptor.cite journal | author = Fathi Z, Corjay MH, Shapira H, Wada E, Benya R, Jensen R, Viallet J, Sausville EA, Battey JF | title = BRS 3: a novel bombesin receptor subtype… …   Wikipedia

  • BLI — bombesin like immunoreactivity …   Medical dictionary

  • BLI — • bombesin like immunoreactivity …   Dictionary of medical acronyms & abbreviations


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