Phenyl salicylate

Phenyl salicylate

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Reference = "Merck Index", 11th Edition, 7282.]
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IUPACName = Phenyl 2-hydroxybenzoate
OtherNames = Salol
Section1 = Chembox Identifiers
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CASNo = 118-55-8
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PubChem = 91558
SMILES = O=C(Oc2ccccc2)c1c(O)cccc1
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Section2 = Chembox Properties
Formula = C13H10O3
MolarMass = 214.22 g/mol
Appearance = White solid
Density = 1.25 g/cm3
MeltingPt = 42 °C
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BoilingPt = 173 °C
Boiling_notes = at 12 mmHg
Solubility = 1 g/6670 mL
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Phenyl salicylate, or salol, is a chemical substance, introduced in 1886 by Marceli Nencki of Basel. It can be created by heating salicylic acid with phenol. It has been used as an intestinal antiseptic based on the antibacterial activity upon hydrolysis in the small intestine. Once used in sunscreens, phenyl salicylate is now used in the manufacture of some polymers, lacquers, adhesives, waxes and polishes. It is also used frequently in school laboratory demonstrations on how cooling rates effect crystal size in igneous rocks.

alol reaction

In the salol reaction, phenyl salicylate reacts with o-toluidine in 1,2,4-trichlorobenzene at elevated temperatures to the corresponding amide "o-Salicylotoluide" [Organic Syntheses, Coll. Vol. 3, p.765 (1955); Vol. 26, p.92 (1946). http://orgsynth.org/orgsyn/pdfs/CV3P0765.pdf] . Salicylamides are a type of drug.

References


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Look at other dictionaries:

  • phenyl salicylate — n a crystalline ester C13H10O3 used chiefly as a stabilizer for cellulosic plastics and vinyl plastics and as an ingredient of suntan preparations because of its ability to absorb ultraviolet light and also as an analgesic and antipyretic called… …   Medical dictionary

  • phenyl salicylate — noun a white powder with a pleasant taste and odor; used to absorb light in sun tan lotions or as a preservative or an antiseptic or a coating for pills in which the medicine is intended for enteric release • Syn: ↑salol • Hypernyms: ↑salicylate… …   Useful english dictionary

  • phenyl salicylate — Chem. salol. * * * …   Universalium

  • salicylate — noun a salt of salicylic acid (included in several commonly used drugs) • Hypernyms: ↑salt, ↑nonsteroidal anti inflammatory, ↑nonsteroidal anti inflammatory drug, ↑NSAID • Hyponyms: ↑aspirin, ↑acetylsalicylic acid …   Useful english dictionary

  • phenyl — The univalent moiety, C6H5–, of benzene. p. alcohol SYN: phenol. p. aminosalicylate a second line antituberculosis drug with a high incidence of hypersensitivity reactions and gastrointestinal upset. p. salicylate …   Medical dictionary

  • PHEN SAL — Phenyl Salicylate (Medical » Physiology) …   Abbreviations dictionary

  • salicylic acid — Chem., Pharm. a white, crystalline, very slightly water soluble powder, C7H6O3, prepared from salicin or phenol: used as a food preservative, in the manufacture of aspirin, and in medicine chiefly in the form of a salicylate as a remedy for… …   Universalium

  • salol — SYN: phenyl salicylate. * * * sal·ol sal .ȯl, .ōl n PHENYL SALICYLATE * * * sa·lol (saґlol) phenyl salicylate …   Medical dictionary

  • salol — /ˈsælɒl/ (say salol) noun a white crystalline substance, phenyl salicylate, C13H10O3, used as an antipyretic, antiseptic, and sunscreen. {sal(icyl) (see salicylate) + ol1} …  

  • salol — noun a white powder with a pleasant taste and odor; used to absorb light in sun tan lotions or as a preservative or an antiseptic or a coating for pills in which the medicine is intended for enteric release • Syn: ↑phenyl salicylate • Hypernyms:… …   Useful english dictionary

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