Weber's syndrome

Weber's syndrome
Weber's syndrome
Classification and external resources

Midbrain cross section showing lesion
ICD-10 G46.3
ICD-9 344.89
DiseasesDB 31247
MeSH D020526

Weber's syndrome (superior alternating hemiplegia) is a form of stroke characterized by the presence of an oculomotor nerve palsy and contralateral hemiparesis or hemiplegia.


Cause and presentation

This lesion is usually unilateral and affects several structures in the midbrain including:

Structure damaged Effect
substantia nigra contralateral parkinsonism because its dopaminergic projections to the basal ganglia innervate the ipsilateral hemisphere motor field, leading to a movement disorder of the contralateral body.
corticospinal fibers contralateral hemiparesis and typical upper motor neuron findings
corticobulbar tract difficulty with contralateral lower facial muscles and hypoglossal nerve functions
oculomotor nerve fibers ipsilateral oculomotor nerve palsy with a drooping eyelid and fixed wide pupil pointed down and out. This leads to diplopia
Human brainstem blood supply description. Posterior cerebral artery is #6, and midbrain is behind it.

It is caused by midbrain infarction as a result of occlusion of the paramedian branches of the posterior cerebral artery or of basilar bifurcation perforating arteries.[1]


It carries the name of Sir Herman David Weber, a German-born physician working in London, who described the condition in 1863.[2][3] It is unrelated to Sturge-Weber syndrome or Klippel-Trenaunay-Weber syndrome.


  1. ^ -932511721 at GPnotebook
  2. ^ Weber HD (1863). "A contribution to the pathology of the crura cerebri". Medico-Chirurgical Transactions 46: 121–139. 
  3. ^ synd/407 at Who Named It?

External links

Wikimedia Foundation. 2010.

См. также в других словарях:

  • Weber-Gubler syndrome — Weber Leyden syndrome Weber s …   Medical dictionary

  • Weber-Gubler syndrome — Web·er Gub·ler syndrome (webґər g bґlər) [Sir H.D. Weber; Adolphe Marie Gubler, French physician, 1821–1879] Weber syndrome …   Medical dictionary

  • Weber-Leyden syndrome — We·ber Ley·den syndrome (webґər liґdən) [Sir H.D. Weber; Ernst Victor von Leyden, German physician, 1832–1910] Weber syndrome …   Medical dictionary

  • Weber-Cockayne syndrome — Web·er Cock·ayne syndrome (vaґbər kok ānґ) [F.P. Weber; Edward Alfred Cockayne, English physician, 1880–1956] the localized form of epidermolysis bullosa simplex …   Medical dictionary

  • Weber-Cockayne syndrome — the localized form of epidermolysis bullosa simplex …   Medical dictionary

  • Klippel-Trenaunay-Weber (KTW) syndrome — A congenital malformation syndrome characterized by the triad of asymmetric limb hypertrophy, hemangiomata, and nevi. "Asymmetric limb hypertrophy" is enlargement of one limb and not the corresponding limb on the other side, the… …   Medical dictionary

  • Weber —  Pour les articles homophones, voir Webber et Veber. Cette page d’homonymie répertorie les différents sujets et articles partageant un même nom. Sommaire 1 …   Wikipédia en Français

  • Syndrome de sturge-weber — CIM 10 : Q85.8 Le syndrome de Sturge Weber (ou SSW) est associé à 10 % des cas d angiome plan de la région frontale et palpébrale supérieure présent à la naissance, au niveau du territoire d innervation du nerf ophtalmique (V 1) Ce n est ni… …   Wikipédia en Français

  • Syndrome de klippel-trenaunay — Le syndrome de Klippel Trenaunay est un syndrome apparaissant dans l enfance et qui se caracterise par l association d une hypertrophie des tissus osseux et mous, d angiomes cutanés et de veines variqueuses. L atteinte est le plus souvent limitée …   Wikipédia en Français

  • Syndrome du burnout — Syndrome d épuisement professionnel Pour les articles homonymes, voir burnout et épuisement. Syndrome d épuisement professionnel CIM 10 : Z73.0 …   Wikipédia en Français

Поделиться ссылкой на выделенное

Прямая ссылка:
Нажмите правой клавишей мыши и выберите «Копировать ссылку»