- Weber's syndrome
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Weber's syndrome Classification and external resources
Midbrain cross section showing lesionICD-10 G46.3 ICD-9 344.89 DiseasesDB 31247 MeSH D020526 Weber's syndrome (superior alternating hemiplegia) is a form of stroke characterized by the presence of an oculomotor nerve palsy and contralateral hemiparesis or hemiplegia.
Contents
Cause and presentation
This lesion is usually unilateral and affects several structures in the midbrain including:
Structure damaged Effect substantia nigra contralateral parkinsonism because its dopaminergic projections to the basal ganglia innervate the ipsilateral hemisphere motor field, leading to a movement disorder of the contralateral body. corticospinal fibers contralateral hemiparesis and typical upper motor neuron findings corticobulbar tract difficulty with contralateral lower facial muscles and hypoglossal nerve functions oculomotor nerve fibers ipsilateral oculomotor nerve palsy with a drooping eyelid and fixed wide pupil pointed down and out. This leads to diplopia Human brainstem blood supply description. Posterior cerebral artery is #6, and midbrain is behind it.It is caused by midbrain infarction as a result of occlusion of the paramedian branches of the posterior cerebral artery or of basilar bifurcation perforating arteries.[1]
History
It carries the name of Sir Herman David Weber, a German-born physician working in London, who described the condition in 1863.[2][3] It is unrelated to Sturge-Weber syndrome or Klippel-Trenaunay-Weber syndrome.
References
- ^ -932511721 at GPnotebook
- ^ Weber HD (1863). "A contribution to the pathology of the crura cerebri". Medico-Chirurgical Transactions 46: 121–139.
- ^ synd/407 at Who Named It?
External links
CNS disease, Vascular disease: Cerebrovascular diseases (G45–G46 and I60–I69, 430–438) Brain ischemia/
cerebral infarction
(ischemic stroke/TIA)precerebral: Anterior spinal artery syndrome · Vertebrobasilar insufficiency (Subclavian steal syndrome)brainstem: medulla (Medial medullary syndrome, Lateral medullary syndrome) · pons (Medial pontine syndrome/Foville's, Lateral pontine syndrome/Millard-Gubler) · midbrain (Weber's, Benedikt, Claude's)GeneralIntracranial hemorrhage
(hemorrhagic stroke)Extra-axialBrainstemAneurysm Other/general Categories:- Stroke
- Disease stubs
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См. также в других словарях:
Weber-Gubler syndrome — Weber Leyden syndrome Weber s … Medical dictionary
Weber-Gubler syndrome — Web·er Gub·ler syndrome (webґər g bґlər) [Sir H.D. Weber; Adolphe Marie Gubler, French physician, 1821–1879] Weber syndrome … Medical dictionary
Weber-Leyden syndrome — We·ber Ley·den syndrome (webґər liґdən) [Sir H.D. Weber; Ernst Victor von Leyden, German physician, 1832–1910] Weber syndrome … Medical dictionary
Weber-Cockayne syndrome — Web·er Cock·ayne syndrome (vaґbər kok ānґ) [F.P. Weber; Edward Alfred Cockayne, English physician, 1880–1956] the localized form of epidermolysis bullosa simplex … Medical dictionary
Weber-Cockayne syndrome — the localized form of epidermolysis bullosa simplex … Medical dictionary
Klippel-Trenaunay-Weber (KTW) syndrome — A congenital malformation syndrome characterized by the triad of asymmetric limb hypertrophy, hemangiomata, and nevi. "Asymmetric limb hypertrophy" is enlargement of one limb and not the corresponding limb on the other side, the… … Medical dictionary
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