Flaviviridae

Flaviviridae

Taxobox
name = "Flaviviridae"
virus_group = iv
familia = "Flaviviridae"
subdivision_ranks = Genera
subdivision = "Flavivirus"
"Pestivirus"
"Hepacivirus"
The "Flaviviridae" are a family of viruses that are primarily spread through arthropod vectors (mainly ticks and mosquitoes). The family gets its name from Yellow Fever virus, a type virus of Flaviviridae; "flavus" means yellow in Latin. (Yellow fever in turn was named because of its propensity to cause jaundice in victims.) [http://microbewiki.kenyon.edu/index.php/Flaviviridae Accessed July 22,2008] .

They include the following genera:
*Genus "Flavivirus" (type species "Yellow fever virus", others include "West Nile virus" and "Dengue Fever")—contains 67 identified human and animal viruses
*Genus "Hepacivirus" (type species "Hepatitis C virus", the single member)
*Genus "Pestivirus" (type species "Bovine virus diarrhea", others include classical swine fever or hog cholera)—contains viruses infecting non-human mammals

"Flaviviridae" have monopartite, linear, single-stranded RNA genomes of positive polarity, 9.6- to 12.3-kilobase in length. The 5'-termini of flaviviruses carry a methylated nucleotide cap, while other members of this family are uncapped and encode an internal ribosome entry site. Virus particles are enveloped and spherical, about 40-60 nm in diameter.

Major diseases caused by the "Flaviviridae" family include:
* Dengue fever
* Japanese encephalitis
* Kyasanur Forest disease
* Murray Valley encephalitis
* St. Louis encephalitis
* Tick-borne encephalitis
* West Nile encephalitis
* Yellow fever
* Hepatitis C Virus Infection

References


Wikimedia Foundation. 2010.


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