- King-Kopetzky syndrome
King-Kopetzky syndrome is an auditory disability with appears clinically as a “normal” hearing threshold. It is also known as "obscure auditory dysfunction (OAD)"The role of a family history in King Kopetzky syndrome (Obscure Auditory Dysfunction). Stephens D., Zhao F.Acta Otolaryngol 2000; 120: 197-200.] or "auditory disability with normal hearing (ADN)", The main reported disability is difficulty in hearing speech in the presence of background noise. [http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=14570238&dopt=Abstract PubMed] ] this is in conjunction with the finding of normal hearing test results.
It was found that King Kopetzky syndrome patients will have a worse Social Hearing Handicap index (SHHI),indicating they suffer a significant degree of speech-hearing disability.Determinants of speech-hearing disability in King Kopetzky syndrome. Zhao F, Stephens D. Scand Audiol.1996;25(2):91-6.]
It seems that somatic anxiety and situations of stress may be determinants of speech-hearing disability.Auditory and psychological factors in ‘auditory disability with normal hearing’. King K, Stephens D. Scand Audiol. 1992;21(2):109-14.]
Some studies indicated an increased prevalence of a family history of hearing impairment in these patients. The pattern of results is suggestive that King-Kopetzky patients may be related to conditions of autosomal dominant inheritance.Audiometric configuration in non-syndromic genetic hearing loss. Liu XZ, Xu L, Newton V. J Audiol Med 3:99-106] Non-syndromic hearing impairment: unparalleled heterogeneity. Van Camp G, Willems PJ, Smith RJH (1997). Am J Genet 60:758-764.]
It was found that based on sensitized measures of auditory dysfunction and on psychological assessment, Subjects could be subdivided into seven subcategories [http://www.medscape.com/medline/abstract/10997453 Zhao F; Stephens D, Subcategories of patient with King-Kopetzky syndrome Br J Audiol .2000;34(4):241-56.] ] .
1- middle ear dysfunction
2- mild cochlear pathology
3- central/medial olivocochlear efferent system (MOCS) auditory dysfunction
4- purely psychological problems
5- multiple auditory pathologies
6- combined auditory dysfunction and psychological problems
Different subgroups may represent different pathogenic and aetiological factors. Thus, subcategorization provides further understanding of the basis of King-Kopetzky syndrome, and hence may guide the rehabilitative management of these patients.
There has been some interest in testing that King-Kopetzky syndrome might be an early stage of late onset familial hearing impairment by Professor
Dafydd Stephens, F Zhao and Angeles Espeso at the Welsh Hearing Institute, Cardiff University.
List of eponymous diseases
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См. также в других словарях:
King-Kopetzky syndrome — see obscure auditory dysfunction … The new mediacal dictionary
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obscure auditory dysfunction — OAD; = King Kopetzky syndrome hearing difficulty, especially in noisy environments, in an individual with a normal audiogram. Treatment includes hearing therapy … The new mediacal dictionary