Chymotrypsinogen

Chymotrypsinogen is a precursor (zymogen) of the digestive enzyme chymotrypsin.

This molecule is inactive and must be cleaved by trypsin, and then by other chymotrypsin molecules, before it can reach its full activity. Its function is to convert proteins to amino acids. The active site of chymotrypsinogen is covered by a 6-amino-acid-long mask. It is only when this mask is removed - when the chymotrypsinogen molecule enters the lumen of the intestine and comes into contact with chymotrypsin molecules - that the enzyme becomes active. This is a very useful safety feature for a protein-digesting enzyme. If chymotrypsinogen were not inactivated in this way, it would digest the pancreas, where it is produced.

References

This enzyme-related article is a stub. You can help Wikipedia by expanding it.v · Categories: Enzymes Enzyme stubs Wikimedia Foundation. 2010. Игры ⚽ Поможем написать реферат Mary Lou Retton Grand National Look at other dictionaries: Chymotrypsinogen — ⇒ Chymotrypsin …   Deutsch wörterbuch der biologie chymotrypsinogen — noun Date: 1933 a zymogen that is secreted by the pancreas and is converted by trypsin to chymotrypsin …   New Collegiate Dictionary chymotrypsinogen — /kuy moh trip sin euh jeuhn, jen /, n. Biochem. a zymogen that is converted by trypsin to chymotrypsin. [1930 35; CHYMOTRYPSIN + O + GEN] * * * …   Universalium chymotrypsinogen — noun An inactive precursor to chymotrypsin …   Wiktionary chymotrypsinogen — The precursor of chymotrypsin. Converted to π chymotrypsin by the action of trypsin. * * * chy·mo·tryp·sin·o·gen .trip sin ə jən n a zymogen that is secreted by the pancreas and is converted by trypsin to chymotrypsin * * * n. see chymotrypsin *… …   Medical dictionary chymotrypsinogen — chy·mo·trypsinogen …   English syllables chymotrypsinogen — n.; see chymotrypsin …   The new mediacal dictionary chymotrypsinogen — /ˌkaɪmoʊtrɪpˈsɪnədʒən/ (say .kuymohtrip sinuhjuhn) noun the inactive precursor of chymotrypsin …   chymotrypsinogen — ˌkīmə+ noun ( s) Etymology: International Scientific Vocabulary chyme + o + trypsinogen : a precursor of a chymotrypsin prepared in crystalline form usually from the pancreas of cattle or hogs and converted by trypsin into a chymotrypsin * * *… …   Useful english dictionary Химотрипсиноген (Chymotrypsinogen) — см. Химотрипсин. Источник: Медицинский словарь …   Медицинские термины 18+ © Academic, 2000-2024 Contact us: Technical Support, Advertising Dictionaries export, created on PHP, Joomla, Drupal, WordPress, MODx. Mark and share Search through all dictionaries Translate… Search Internet Share the article and excerpts Direct link … Do a right-click on the link above and select “Copy Link”