Basal body


Basal body

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A basal body (sometimes basal granule or kinetosome) is an organelle formed from a centriole, a short cylindrical array of microtubules. It is found at the base of a eukaryotic undulipodium (cilium or flagellum) and serves as a nucleation site for the growth of the axoneme microtubules. Centrioles, from which basal bodies are derived, act as anchoring sites for proteins that in turn anchor microtubules within centrosomes, one type of microtubule organizing center (MTOC). These microtubules provide structure and facilitate movement of vesicles and organelles within many eukaryotic cells. Basal bodies, however, are specifically the bases for cilia and flagella that extend out of the cell.

Basal bodies are derived from centrioles through a largely mysterious process. They are structurally the same, each containing a microtubules triplet 9+0 helocoidal configuration forming a hollow cylinder.

Regulation of basal body production and spatial orientation is a function of the nucleotide-binding domain of γ-tubulin (Shang et al, 2005).

References

Boston University Medical Histoloy: Ultrastructure of the Cell

Y. Shang, C.-C. Tsao, and M. A. Gorovsky. 2005. Mutational analyses reveal a novel function of the nucleotide-binding domain of gamma-tubulin in the regulation of basal body biogenesis. "J. Cell Biol." 171(6):1035-44. PMID 16344310

External links

* - "Ultrastructure of the Cell: ciliated epithelium, cilia and basal bodies"


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Look at other dictionaries:

  • basal body — n a minute distinctively staining cell organelle found at the base of a flagellum or cilium and resembling a centriole in structure called also basal granule, kinetosome * * * one of the cylindrical cytoplasmic bodies structurally resembling the… …   Medical dictionary

  • basal body — noun Date: 1902 a minute distinctively staining cell organelle found at the base of a flagellum or cilium and identical to a centriole in structure called also basal granule, kinetosome …   New Collegiate Dictionary

  • basal body — The cylindrical structure at the base of procaryotic and eucaryotic flagella that attaches them to the cell …   Dictionary of microbiology

  • basal body — Structure found at the base of eukaryotic cilia and flagella consisting of a continuation of the nine outer sets of axonemal microtubules but with the addition of a C tubule to form a triplet (like the centriole). May be self replicating and… …   Dictionary of molecular biology

  • basal body — Cell Biol. a cylindrical organelle, within the cytoplasm of flagellated and ciliated cells, that contains microtubules and forms the base of a flagellum or cilium: identical in internal structure to a centriole. [1900 05] * * * …   Universalium

  • basal body — noun A cellular organelle, similar to a centriole, associated with the formation of cilia and flagella …   Wiktionary

  • basal body — ba′sal bod′y n. cbl an organelle of ciliated or flagellated cells that forms the base of the cilia or flagella • Etymology: 1900–05 …   From formal English to slang

  • basal body — noun 1. : a minute distinctively staining cell organelle found at the base of a flagellum or cilium and resembling a centriole in structure called also blepharoplast 2. : kinetoplast …   Useful english dictionary

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