Pyknosis


Pyknosis
Morphological characteristics of pyknosis and other forms of nuclear destruction

Pyknosis, or karyopyknosis, is the irreversible condensation of chromatin in the nucleus of a cell undergoing necrosis[1] or apoptosis.[2] It is followed by karyorrhexis, or fragmentation of the nucleus. Pyknosis (from Greek pyknono meaning "to thicken up, to close or to condense") is also observed in the maturation of erythrocytes (a red blood cell) and the neutrophil (a type of white blood cell). The maturing metarubricyte (a stage in RBC maturation) will condense its nucleus before expelling it to become a reticulocyte. The maturing neutrophil will condense its nucleus into several connected lobes that stay in the cell until the end of its cell life.

Pyknotic nuclei are often found in the zona reticularis of the adrenal gland.

See also

References

  1. ^ Kumar V, Abbas A, Nelson F, Mitchell R. (2007). "Robbins Basic Pathology". Robbins Basic Pathology: 6, 9–10. 
  2. ^ Kroemer G, Galluzzi L, Vandenabeele P, et al. (January 2009). "Classification of cell death: recommendations of the Nomenclature Committee on Cell Death 2009". Cell Death Differ. 16 (1): 3–11. doi:10.1038/cdd.2008.150. PMC 2744427. PMID 18846107. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=2744427. 



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Look at other dictionaries:

  • pyknosis — [pik nō′sis] n. pl. pyknoses [pyk no′sēz΄] a process of thickening, esp. in the shrinking nucleus of a degenerating cell pyknotic [pyknät′ik] adj. * * * …   Universalium

  • pyknosis — [pik nō′sis] n. pl. pyknoses [pyk no′sēz΄] a process of thickening, esp. in the shrinking nucleus of a degenerating cell pyknotic [pyknät′ik] adj …   English World dictionary

  • pyknosis — A thickening or condensation; specifically, a condensation and reduction in size of the cell or its nucleus, usually associated with hyperchromatosis; nuclear p. is a stage of necrosis. [pykno + G. osis, condition] * * * pyk·no·sis also… …   Medical dictionary

  • pyknosis — Contraction of nuclear contents to a deep staining irregular mass; sign of cell death …   Dictionary of molecular biology

  • pyknosis — noun In biology, shrinkage and condensing, such as that of a dying cell or the appearance of a cells nucleus …   Wiktionary

  • pyknosis — n. the process in which the cell nucleus is thickened into a dense mass, which occurs when cells die. Derivatives: pyknotic adj …   The new mediacal dictionary

  • pyknosis — noun a degenerative state of the cell nucleus • Syn: ↑pycnosis • Derivationally related forms: ↑pyknotic, ↑pycnotic (for: ↑pycnosis) • Hypernyms: ↑disease …   Useful english dictionary

  • Пикноз (Pyknosis) — конденсация ядра клетки, сопровождающаяся его сморщиванием в однородную гиперхромную плотную массу; обычно этот процесс наблюдается при гибели клетки. Пикнотнчный (pyknotic). Источник: Медицинский словарь …   Медицинские термины

  • ПИКНОЗ — (pyknosis) конденсация ядра клетки, сопровождающаяся его сморщиванием в однородную гиперхромную плотную массу; обычно этот процесс наблюдается при гибели клетки. Пикнотнчный (pyknotic) …   Толковый словарь по медицине

  • pycnotic — adjective of or relating to or exhibiting pyknosis • Syn: ↑pyknotic • Pertains to noun: ↑pyknosis, ↑pyknosis (for: ↑pyknotic) • Derivationally related forms: ↑p …   Useful english dictionary


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