Hyperkeratinization is a disorder of the cells lining the inside of a hair follicle. It is the normal function of these cells to detach or slough off () from the skin lining at normal intervals. The dead cells are then forced out of the follicle (primarily by the growing hair). However, in hyperkeratinization, this process is interrupted and a number of these dead skin cells do not leave the follicle because of an excess of keratin, a natural protein found in the skin. This excess of keratin, which is influenced by genetics, results in an increased adherence/bonding of dead skin cells together. This cohesion of cells will block or "cap" the hair follicle (leading to keratosis pilaris) or clog the sebaceous/oil duct (leading to acne).

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  • hyperkeratinization — SYN: hyperkeratosis. * * * hy·per·ke·ra·ti·ni·za·tion .ker ət ə nə zā shən, kə .rat ən ə n HYPERKERATOSIS * * * hy·per·ker·a·tin·iza·tion (hi″pər ker″ə tin″ĭ zaґshən) [hyper + keratinization] the excessive… …   Medical dictionary

  • hyperkeratinization — hy·per·keratinization …   English syllables

  • hyperkeratinization — “+ noun Etymology: hyper + keratinization : hyperkeratosis …   Useful english dictionary

  • Acne vulgaris — This article is about a skin disease commonly found during adolescence. For other acneform skin diseases, see Acne (disambiguation). Acne vulgaris Classification and external resources …   Wikipedia

  • Keratosis pilaris — Classification and external resources Keratosis pilaris rubra on a right upper arm. ICD 9 …   Wikipedia

  • Hyperkeratosis — Infobox Disease Name = PAGENAME Caption = DiseasesDB = 20624 ICD10 = ICD9 = ICD9|701.1 ICDO = OMIM = MedlinePlus = eMedicineSubj = eMedicineTopic = MeshID = Hyperkeratosis results when an excess of proteins called keratins are produced. In humans …   Wikipedia

  • Plantar hyperkeratosis — is a condition of the sole of the foot, wherein the skin is abnormally thickened. It is recommended [ [http://www.thedoctorsdoctor.com/diseases/keratodermas.htm thedoctorsdoctor.com article] ] to surgically remove the dead skin, to provide… …   Wikipedia

  • hyperkeratosis — Thickening of the horny layer of the epidermis or mucous membrane. SEE ALSO: keratoderma, keratosis. SYN: hyperkeratinization. h. congenita SYN: ichthyosis vulgaris. diffuse h. of palms and soles an …   Medical dictionary

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