- Liver disease
Name = PAGENAME
MeshID = D008107
Liver disease is a broad term describing any number of
diseases affecting the liver. Many are accompanied by jaundicecaused by increased levels of bilirubinin the system. The bilirubin results from the breakup of the hemoglobinof dead red blood cells; normally, the liver removes bilirubin from the blood and excretes it through bile.
Hepatitis, inflammation of the liver, caused mainly by various viruses but also by some poisons, autoimmunity or hereditary conditions.
Cirrhosisis the formation of fibrous tissue in the liver, replacing dead liver cells. The death of the liver cells can for example be caused by viral hepatitis, alcoholismor contact with other liver-toxic chemicals.
Haemochromatosis, a hereditary disease causing the accumulation of ironin the body, eventually leading to liver damage.
Cancerof the liver (primary hepatocellular carcinomaor cholangiocarcinomaand metastatic cancers, usually from other parts of the gastrointestinal tract).
Wilson's disease, a hereditary diseasewhich causes the body to retain copper.
Primary sclerosing cholangitis, an inflammatory disease of the bile duct, likely autoimmune in nature.
Primary biliary cirrhosis, autoimmune disease of small bile ducts.
Budd-Chiari syndrome, obstruction of the hepatic vein.
Gilbert's syndrome, a genetic disorder of bilirubinmetabolism, found in about 5% of the population.
Glycogen storage disease type II, the build-up of glycogen causes progressive muscle weakness (myopathy) throughout the body and affects various body tissues, particularly in the heart, skeletal muscles, liver and nervous system.
There are also many pediatric liver disease, including
biliary atresia, alpha-1 antitrypsin deficiency, alagille syndrome, and progressive familial intrahepatic cholestasis, to name but a few.
A number of
liver function testsare available to test the proper function of the liver. These test for the presence of enzymes in blood that are normally most abundant in liver tissue, metabolites or products.
ymptoms of a diseased liver
The external signs include a coated tongue, bad breath, skin rashes, itchy skin, excessive sweating, offensive body odour, dark circles under the eyes, red swollen and itchy eyes, acne
rosacea, brownish spots and blemishes on the skin, flushed facial appearance or excessive facial blood vessels. [ [http://www.liverdoctor.com/index.php?page=symptoms Dr Sandra Cabot - The Liver Doctor] ] Other symptoms include jaundice, dark urine, pale stool, bone loss, easy bleeding, itching, small, spider-like blood vessels visible in the skin, enlarged spleen, fluid in the abdominal cavity, chills, pain from the biliary tract or pancrea, and an enlarged gallbladder. [ [http://www.umm.edu/liver/common.htm University of Maryland - Symptoms of Liver Disease] ]
The symptoms related to liver dysfunction include both physical signs and a variety of symptoms related to digestive problems, blood sugar problems, immune disorders, abnormal absorption of fats, and metabolism problems. [ [http://www.liverdoctor.com/index.php?page=symptoms Dr Sandra Cabot - The Liver Doctor] ]
The malabsorption of fats may lead to symptoms that include indigestion, reflux, hemorrhoids, gall stones, intolerance to fatty foods, intolerance to alcohol, nausea and vomiting attacks, abdominal bloating, and constipation.
Nervous system disorders include depression, mood changes, especially anger and irritability, poor concentration and "
foggy brain," overheating of the body, especially the face and torso, and recurrent headaches (including migraine) associated with nausea.
The blood sugar problems include a craving for sugar, hypoglycaemia and unstable blood sugar levels, and the onset of
type 2 diabetes.
Abnormalities in the level of fats in the blood stream include elevated LDL cholesterol, reduced HDL cholesterol, elevated triglycerides, clogged arteries leading to high blood pressure heart attacks and strokes, build up of fat in other body organs (fatty degeneration of organs), lumps of fat in the skin (lipomas and other fatty tumors), excessive weight gain (which may lead to obesity), inability to lose weight even while dieting, sluggish metabolism, protuberant abdomen (pot belly), cellulite, fatty liver, and a roll of fat around the upper abdomen (liver roll). [ [http://www.liverdoctor.com/index.php?page=symptoms Dr Sandra Cabot - The Liver Doctor] ]
Treatment of liver diseases
- The most commonly used herbs for liver problems include
Milk Thistle, Sho-saiko-to, DandelionRoot, LicoriceRoot, and Chicoryroot. [Prescription for Natural Cures, Dr. James F. Balch, 2004, pages 302-304] - Milk Thistle[ [http://www.mskcc.org/mskcc/html/69303.cfm Milk Thistle: Memorial Sloan-Kettering Cancer Center] ] is the best studied herb for hepatitis, and has been shown to help protect and regenerate liver cells. [Prescription for Natural Cures, Dr. James F. Balch, 2004, page 615]
* [http://www.eliver.org Liver disease types, symptoms and detailed information]
Wikimedia Foundation. 2010.
Look at other dictionaries:
liver disease — noun a disease affecting the liver • Hypernyms: ↑disease • Hyponyms: ↑cirrhosis, ↑cirrhosis of the liver, ↑fatty liver, ↑hepatitis, ↑liver cancer, ↑cancer of the liver … Useful english dictionary
Non-alcoholic fatty liver disease — Classification and external resources Micrograph of non alcoholic fatty liver disease, demonstrating marked macrovesicular steatosis. Trichrome stain … Wikipedia
Chronic liver disease — in the clinical context is a disease process of the liver that involves a process of progressive destruction and regeneration of the liver parenchyma leading to fibrosis and cirrhosis. Contents 1 Causes 2 Complications of chronic liver disease … Wikipedia
Model for End-Stage Liver Disease — The Model for End Stage Liver Disease, or MELD, is a scoring system for assessing the severity of chronic liver disease. It was initially developed to predict death within three months of surgery in patients who had undergone a transjugular… … Wikipedia
Children's Liver Disease Foundation — (CLDF) is a UK charity whose purpose is fighting childhood liver disease and raising awareness of childhood liver disease amongst the general public. CLDF was founded in 1980 by the parents of a little boy named Michael McGough, who died before… … Wikipedia
Polycystic liver disease — Classification and external resources Micrograph showing a von Meyenburg complex, a bile duct hamartoma associated with polycystic liver disease. Trichrome stain … Wikipedia
Metastatic liver disease — Micrograph of a liver core needle biopsy showing metastatic cancer … Wikipedia
Alcoholic liver disease — is the major cause of liver disease in Western countries, (in Asian countries, viral hepatitis is the major cause). It arises from the excessive ingestion of alcohol. PathophysiologyFatty change and alcoholic hepatitis are probably reversible.… … Wikipedia
Pediatric end-stage liver disease — (PELD) is a disease severity scoring system for children under 12 years of age. It is calculated from the patient s albumin, bilirubin, and international normalized ratio (INR) together with the patient s age and degree of growth failure. This… … Wikipedia
big liver disease — noun : that form of avian leukosis in which the liver is greatly enlarged and infiltrated with white blood cells; broadly : avian leukosis complex * * * big liver disease, a form of lymphomatosis characterized by enlargement of the liver … Useful english dictionary