Hydrophobin


Hydrophobin

Pfam_box
Symbol = Hydrophobin_2
Name = Fungal hydrophobin



width =250
caption =Structure of hydrophobin HFBI from "Trichoderma reesei"
Pfam= PF06766
InterPro= IPR010636
SMART=
PROSITE = PDOC00739
SCOP = 1r2m
TCDB =
OPM family=
OPM protein= 1r2m
PDB=PDB3|1r2mB:17-82

Hydrophobins are a class of small, cysteine rich proteins (~ 100 amino acids) that are expressed only by filamentous fungi. They are known for their capability of forming a hydrophobic (water-repellent) coating on a surface of an object. They were first discovered and separated in "Schizophyllum commune" in 1991. Based on differences in hydropathy patterns and biophysical properties, they are divided into two categories: class I and class II.

Fungi make complex aerial structures and spores even in aqueous environments.

The fungal hydrophobins seem to be restricted to ascomycetes. Hydrophobins are generally found on the outer surface of conidia and of the hyphal wall, and may be involved in mediating contact and communication between the fungus and its environmentcite journal |author=Whiteford JR, Spanu PD |title=The hydrophobin HCf-1 of Cladosporium fulvum is required for efficient water-mediated dispersal of conidia |journal=Fungal Genet. Biol. |volume=32 |issue=3 |pages=159–168 |year=2001 |pmid=11343402 |doi=10.1006/fgbi.2001.1263] . Some family members contain multiple copies of the domain.

References

Further reading

* cite paper
author = Scholtmeijer, Karin
title = Expression and engineering of hydrophobin genes
publisher = University of Groningen
date = 2000
url = http://irs.ub.rug.nl/ppn/240088549

* cite journal
author = J. Hakanpää, A. Paananen, S. Askolin, T. Nakari-Setälä, T. Parkkinen, M. Penttilä, M. B. Linder, J. Rouvinen
title = Atomic Resolution Structure of the HFBII Hydrophobin, a Self-assembling Amphiphile
journal = The Journal of Biological Chemistry
volume = 279
issue = 1
pages = 534–539
year = 2004
doi = 10.1074/jbc.M309650200

* cite journal
author = H. A. B. Wösten, M. L. de Vocht
title = Hydrophobins, the fungal coat unravelled
journal = Biochimica et Biophysica Acta (BBA) - Reviews on Biomembranes
volume = 1469
issue = 2
pages = 79–86
year = 2000
doi = 10.1016/S0304-4157(00)00002-2


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