- Koplik's spots
Koplik's spots (kop'liks) are small, irregular, red spots with a minute bluish white speck in the center of each seen on the buccal mucosa and lingual mucosa (
mucous membraneof the inside of the cheek and tongue) and are pathognomonicof early stage measles. They are named after Henry Koplik(1858-1927), an American pediatricianwho first described them in 1896.
They often appear a few days before the rash arrives and can be a useful sign to look for in children known to be exposed to the
The first description of these spots by some authors are ascribed to Reubold, Würzburg 1854, by others to Johann Andreas Murray (1740-1791). Before Koplik, the German internist
Carl Jakob Adolf Christian Gerhardt(1833-1902) in 1874, the Danish physician N. Flindt in 1879, and the Russian Nicolai Feodorowitsch von Filatov (1847-1902) in 1897, had observed equivalent phenomena.Koplik, H. The diagnosis of the invasion of measles from a study of the exanthema as it appears on the buccal mucous membrane. Archives of Pediatrics, New York, 1896; 13: 918-922." (accessed from http://www.whonamedit.com/synd.cfm/1437.html on 9/13/2006)]
* [http://www.dentistry.leeds.ac.uk/oralpath/viruses/viral%20infections/340%20images/other%20viral%20images/koplik%27s%20spots.jpgImage of Koplik's spots] - dentistry.leeds.ac.uk.
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Koplik's spots — Kop·lik s spots käp liks or Kop·lik spots lik n pl small bluish white dots surrounded by a reddish zone that appear on the mucous membrane of the cheeks and lips before the appearance of the skin eruption in a case of measles Koplik Henry (1858… … Medical dictionary
Koplik's spots — noun small red spots with white centers found on the mucous membranes of the mouth and tongue; symptom of measles that appears one or two days before the measles rash appears • Hypernyms: ↑symptom * * * ˈkäpliks noun plural also koplik spots… … Useful english dictionary
Koplik’s spots — Little spots inside the mouth that are highly characteristic of the early phase of measles (rubeola). The spots look like a tiny grains of white sand, each surrounded by a red ring. They are found especially on the inside of the cheek (the buccal … Medical dictionary
Koplik's spots — /kop liks/, (in measles) small pale spots with reddish rims that appear on the lips and mucous membranes inside the cheeks before the skin eruption takes place. [1895 1900; named after Henry Koplik (1858 1927), U.S. pediatrician] * * * … Universalium
Koplik's spots — small red spots with bluish white centres that often appear on the mucous membranes of the mouth in measles. [Koplik (1858–1927), US physician] … The new mediacal dictionary
Koplik's spots — red spots surrounded with white areas that appear in the mouth during the early stages of measles (Medicine) … English contemporary dictionary
Koplik's spots — (kop liks) Lesions of the oral cavity caused by the measles (rubeola) virus that are characterized by a bluish white speck in the center of each … Dictionary of microbiology
Пятна Коплика (Koplik'S Spots) — небольшие красные пятна с синевато беловатой окраской в центре, которые часто появляются на слизистой оболочке полости рта у больных корью. Источник: Медицинский словарь … Медицинские термины
KOPLIK, HENRY — (1858–1927), U.S. pediatrician. Koplik, who was born in New York, became assistant professor of pediatrics at Bellevue Medical College as well as consulting physician to other New York hospitals. Koplik is known as the discoverer of the… … Encyclopedia of Judaism
koplik spots — noun plural see koplik s spots … Useful english dictionary