Bucladesine


Bucladesine
Bucladesine
Systematic (IUPAC) name
sodium (3aR,4R,6R,6aR)-4-(6-butanamido-9H-purin-9-yl)-6-[(butanoyloxy)methyl]-2-oxo-tetrahydro-2H-1,3,5,2λ5-furo[3,4-d][1,3,2]dioxaphosphol-2-olate
Clinical data
AHFS/Drugs.com International Drug Names
Pregnancy cat.  ?
Legal status  ?
Identifiers
CAS number 362-74-3
ATC code C01CE04
PubChem CID 28177
ChemSpider 9306 YesY
UNII 63X7MBT2LQ YesY
ChEBI CHEBI:50095 YesY
ChEMBL CHEMBL485980 YesY
Synonyms • Dibutyryl cyclic adenosine monophosphate
• (N6,2'-O-dibutyryl)-adenosine-3',5'-mono-phosphate
• Dibutyryl cAMP
• DcAMP
• DBcAMP
Chemical data
Formula C18H23N5NaO8P 
Mol. mass 491.368 g/mol
SMILES eMolecules & PubChem
 YesY(what is this?)  (verify)

Bucladesine is a cyclic nucleotide derivative which mimics the action of endogenous cAMP and is a phosphodiesterase inhibitor.

Bucladesine is a cell permeable cAMP analog. The compound is used in a wide variety of research applications because it mimics cAMP and can induce normal physiological responses when added to cells in experimental conditions. cAMP is only able to elicit minimal responses in these situations.

External links