Virchow's node

Virchow's node

Infobox Lymph
Name = Virchows node
Latin =
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Caption = Regional lymph tissue. (Supraclavicular near top, in green.)⋅

Caption2 = Deep Lymph Nodes
1. Submental
2. Submandibular (Submaxillary)

Anterior Cervical Lymph Nodes (Deep)
3. Prelaryngeal
4. Thyroid
5. Pretracheal
6. Paratracheal

Deep Cervical Lymph Nodes
7. Lateral jugular
8. Anterior jugular
9. Jugulodigastric

Inferior Deep Cervical Lymph Nodes
10. Juguloomohyoid
11. Supraclavicular (scalene)
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In medicine (oncology), Virchow's node (or signal node) is an enlarged, hard, left supraclavicular lymph node which can contain metastasis of visceral (abdominal) malignancy.

Clinical significance

Malignancies of the internal organs can reach an advanced stage before giving symptoms. Stomach cancer, for example, can remain symptomless while metastatizing. One of the first visible spots where these tumors metastatise is the left supraclavicular lymph node. The left supraclavicular node is the classical Virchow's node because it is on the left side of the neck where the lymphatic drainage of most of the body (from the thoracic duct) enters the venous circulation via the left subclavian vein.

Differential diagnosis of an enlarged Virchow's node includes lymphoma, various intra-abdominal malignancies, breast cancer, lung cancer, and infection (e.g. of the arm).


It is named after Rudolf Virchow (1821-1902), the German pathologist who first described the association. The presence of an enlarged Virchow's node is also referred to as Troisier's sign, named after Charles Emile Troisier, who also described this.

Because an enlarged Virchow's node is often a harbinger of malignant disease, it is sometimes called the "sentinel node". This needs to be contrasted with the technique of sentinel lymph node biopsy. It should also not be confused with the 'sentinel gland' of the greater omentum. [eMedicineDictionary|sentinel+gland]



External links


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См. также в других словарях:

  • Virchow's node — n SIGNAL NODE …   Medical dictionary

  • Node — Literally a knot, a node is a collection of tissue. For example a lymph node, is a collection of lymphoid tissue. A nodule is a small node, a little collection of tissue. * * * 1. A knob or nodosity; a circumscribed swelling; in anatomy, a… …   Medical dictionary

  • Virchow angle etc. — Vir·chow angle, etc. (fērґko) [R.L.K. Virchow] see under angle, crystal, granulation, line and triad; see lepra cell, under cell; see corneal corpuscles, under corpuscle; and see signal node, under node …   Medical dictionary

  • Virchow — Rudolf L.K., German pathologist and politician, 1821–1902. See V. angle, V. cells, under cell, V. corpuscles, under corpuscle, V. crystals, under crystal, V. disease, V. node, V. psammoma, V. Holder angle, V. Hassall bodies, under body, V. Robin… …   Medical dictionary

  • Virchow gland — signal node …   Medical dictionary

  • Rudolf Virchow — Rudolph Carl Virchow Rudolph Virchow Born 13 October 1821 Schivelbein, Pomerania …   Wikipedia

  • Lymph node — A Lymph node (] MedullaThere are two named structures in the medulla: * The medullary cords are cords of lymphatic tissue, and include plasma cells and B cells * The medullary sinuses (or sinusoids ) are vessel like spaces separating the… …   Wikipedia

  • signal node — sig·nal node sig nəl n a supraclavicular lymph node which when tumorous is often a secondary sign of gastrointestinal cancer called also Virchow s node * * * an enlarged supraclavicular lymph node that is often the first sign of an abdominal… …   Medical dictionary

  • Troisier node — Virchow node signal n …   Medical dictionary

  • lymph node — One of numerous round, oval, or bean shaped bodies located along the course of lymphatic vessels, varying greatly in size (1–25 mm in diameter) and usually presenting a depressed area, the hilum, on one side through which blood vessel s enter and …   Medical dictionary

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