Ductus arteriosus

Ductus arteriosus
Artery: Ductus arteriosus
Gray502.png
Plan of the fetal circulation. ("Ductus arteriosus" visible at upper right.)
Patent ductus arteriosus.jpg
Heart cross-section with PDA
Gray's subject #139 540
Source pulmonary artery   
Branches aortic arch
Vein ductus venosus
Precursor aortic arch 6
MeSH Ductus+Arteriosus

In the developing fetus, the ductus arteriosus (DA), also called the ductus Botalli, is a shunt connecting the pulmonary artery to the aortic arch. It allows most of the blood from the right ventricle to bypass the fetus's fluid-filled lungs. Upon closure at birth, it becomes the ligamentum arteriosum. There are two other fetal shunts, the ductus venosus and the foramen ovale.

Patent ductus arteriosus

Failure of a child's DA to close after birth results in a condition called patent ductus arteriosus and the generation of a left-to-right shunt. If left uncorrected, patency leads to pulmonary hypertension and possibly congestive heart failure and cardiac arrhythmias. Prostaglandins are responsible for maintaining the ductus arteriosus. Closure may be induced with NSAIDs because these drugs inhibit prostaglandin synthesis.

A patent ductus arteriosus affects around 40% of infants with Down syndrome (DS). A failure to thrive is a very common sign of this condition.[1]

References

  1. ^ Pritchard & Korf. "Medical Genetics at a Glance". Blackwell Publishing. 2010. p63.

External links

  • Circulatory changes at birth at berkeley.edu
  • [1] Ambient Air Pollution and Cardiovascular Malformations in Atlanta Georgia. This is a study showing a correlation between air pollution, particulate matter greater than 10 micrometers, that has statistical significance in increasing the risk of patent ductus arteriosus when inhaled by pregnant women at 3-7 weeks of pregnancy.

Wikimedia Foundation. 2010.

См. также в других словарях:

  • Ductus arteriosus — Saltar a navegación, búsqueda El Ductus Arteriosus o conducto arterioso de Botal es un conducto situado en la parte inferior de la concavidad de la arteria aorta, comunicando con la arteria pulmonar, y que se encuentra presente en el ser humano… …   Wikipedia Español

  • ductus arteriosus — conducto arterioso Diccionario ilustrado de Términos Médicos.. Alvaro Galiano. 2010 …   Diccionario médico

  • Ductus arteriosus — Herz eines Hundes, Nr. 6 zum Ligamentum arteriosum zurückgebildeter Ductus arteriosus Der Ductus arteriosus (auch Ductus arteriosus Botalli oder Ductus Botalli genannt), stellt im fetalen (vorgeburtlichen) Blutkreislauf eine Verbindung zwischen… …   Deutsch Wikipedia

  • Ductus arteriosus — A key arterial shunt (ductus) in fetal life. Before birth, blood pumped from the heart through the pulmonary artery toward the lungs is shunted into the aorta. This arterial shunt is a short vessel called the ductus arteriosus. When the shunt is… …   Medical dictionary

  • ductus arteriosus — Channel between the pulmonary artery and the aorta in the fetus, which bypasses the lungs to distribute oxygen received through the placenta from the mother s blood. It normally closes once the baby is born and the lungs inflate, separating the… …   Universalium

  • ductus arteriosus — a blood vessel in the fetus connecting the pulmonary artery directly to the ascending aorta, so bypassing the pulmonary circulation. It normally closes after birth. Failure of the ductus to close (patent ductus arteriosus) produces a continuous… …   The new mediacal dictionary

  • ductus arteriosus — noun a blood vessel in a fetus that bypasses pulmonary circulation by connecting the pulmonary artery directly to the ascending aorta; normally closes at birth • Hypernyms: ↑blood vessel • Hyponyms: ↑patent ductus arteriosus • Part Holonyms:… …   Useful english dictionary

  • Ductus arteriosus — arterinis latakas statusas T sritis gyvūnų anatomija, gyvūnų morfologija atitikmenys: lot. Ductus arteriosus ryšiai: platesnis terminas – kairioji plaučių arterija …   Veterinarinės anatomijos, histologijos ir embriologijos terminai

  • Ductus arteriosus — arterinis latakas statusas T sritis gyvūnų raida, augimas, ontogenezė, embriologija atitikmenys: lot. Ductus arteriosus ryšiai: platesnis terminas – šeštasis aortos lankas siauresnis terminas – arterinis raištis …   Veterinarinės anatomijos, histologijos ir embriologijos terminai

  • Ductus arteriosus — arterinis latakas statusas T sritis embriologija atitikmenys: lot. Ductus arteriosus ryšiai: platesnis terminas – šeštasis aortos lankas siauresnis terminas – arterinis raištis …   Medicininės histologijos ir embriologijos vardynas


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