- Vector (biology)
epidemiology, a vector is an organismthat does not cause diseaseitself but which transmits infectionby conveying pathogens from one host to another.
A classic example is the anopheles mosquito which acts as a vector for the disease
malariaby transmitting the malarial parasite plasmodiumto humans.In this case plasmodiumis harmless to the mosquito (its intermediate host) but causes the disease malariain humans (its definitive host).
molecular biologyand genetic engineeringa vector is a vehicle for transferring genetic material into a cell.
viral vectoris a virus which has been modified to transduct specific genetic material into a cell, e.g. for gene therapy.
A plasmid vector is made by splicing a
DNA constructinto a plasmid. Various techniques are then used to transfect the plasmid into the cell.
There are two types of vector that convey infectious organisms to a host: mechanical and biological. Microbes do not multiply within mechanical vectors - mechanical vectors only physically transport microbes from host to host. In contrast, microbes must propagate within a biological vector before the biological vector can transmit the microbes.
mosquito( malaria, St. Louis encephalitis, dengue fever, yellow fever, West Nile virus)
flea( bubonic plague)
tick( Lyme disease, rocky mountain spotted fever, tick-borne encephalitis)
deer mouse( hantavirus)
kissing bug( Triatominae) ( Chagas Disease)
Cell transformation and gene therapy
tobacco mosaic virus(plants)
SV40(Simian virus 40)
Yeast artificial chromosome( Chromosome walking, Positional cloning)
Bacterial artificial chromosome( Shotgun sequencing)
* cite news
World Health Organization, Global Malaria Programme
* cite news
publisher=Centers for Disease Control and Prevention
* [http://www.genetherapynet.com Gene Therapy Net]
* [http://vectorbio.rutgers.edu The Rutgers University Center for Vector Biology]
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