Deoxyguanosine triphosphate


Deoxyguanosine triphosphate
Deoxyguanosine triphosphate
Identifiers
PubChem 65103
ChemSpider 58613 YesY
ChEBI CHEBI:16497 N
ChEMBL CHEMBL477486 N
Jmol-3D images Image 1
Properties
Molecular formula C10H16N5O13P3
Molar mass 507.181023
 N (verify) (what is: YesY/N?)
Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
Infobox references

Deoxyguanosine triphosphate[1] (dGTP) is a nucleoside triphosphate, and a nucleotide precursor used in cells for DNA synthesis. The substance is used in the polymerase chain reaction technique, in sequencing, and in cloning. It is also the competitor of inhibition onset by acyclovir in the treatment of HSV virus.[2]

References

  1. ^ Nelson, David L.; Cox, Michael M. (2005), Principles of Biochemistry (4th ed.), New York: W. H. Freeman, ISBN 0-7167-4339-6 
  2. ^ Furman PA, Lambe CU, Nelson DJ (July 1982). "Effect of acyclovir on the deoxyribonucleoside triphosphate pool levels in Vero cells infected with herpes simplex virus type 1". Am. J. Med. 73 (1A): 14–7. doi:10.1016/0002-9343(82)90056-0. PMID 6285704.