Kv1.1


Kv1.1

protein
Name = potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia)
caption =


width =
HGNCid = 6218
Symbol = KCNA1
AltSymbols = Kv1.1, RBK1, HUK1, MBK1, AEMK
EntrezGene = 3736
OMIM = 176260
RefSeq = NM_000217
UniProt = Q09470
PDB =
ECnumber =
Chromosome = 12
Arm = p
Band = 13
LocusSupplementaryData =

Kv1.1 is a shaker related voltage-gated potassium channel encoded by the gene|KCNA1 gene.cite journal | author = Curran ME, Landes GM, Keating MT | title = Molecular cloning, characterization, and genomic localization of a human potassium channel gene | journal = Genomics | volume = 12 | issue = 4 | pages = 729–37 | year = 1992 | pmid = 1349297 | doi = 10.1016/0888-7543(92)90302-9  | issn = ] cite journal | author = Albrecht B, Weber K, Pongs O | title = Characterization of a voltage-activated K-channel gene cluster on human chromosome 12p13 | journal = Recept. Channels | volume = 3 | issue = 3 | pages = 213–20 | year = 1995 | pmid = 8821794 | doi = | issn = ] cite journal | author = Gutman GA, Chandy KG, Grissmer S, Lazdunski M, McKinnon D, Pardo LA, Robertson GA, Rudy B, Sanguinetti MC, Stühmer W, Wang X | title = International Union of Pharmacology. LIII. Nomenclature and molecular relationships of voltage-gated potassium channels | journal = Pharmacol. Rev. | volume = 57 | issue = 4 | pages = 473–508 | year = 2005 | pmid = 16382104 | doi = 10.1124/pr.57.4.10 | issn = ] The Isaacs syndrome is a result of an autoimmune reaction against the Kv1.1 ion channel .cite journal | author = Newsom-Davis J | title = Autoimmune neuromyotonia (Isaacs' syndrome): an antibody-mediated potassium channelopathy | journal = Ann. N. Y. Acad. Sci. | volume = 835 | issue = | pages = 111–9 | year = 1997 | pmid = 9616766 | doi = | issn = | url = http://www.annalsnyas.org/cgi/reprint/835/1/111 ]

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