- Vincamine
drugbox
IUPAC_name = (3α,14β,16α)-14,15-dihydro-
14-hydroxyeburnamenine-14-carboxylic acid methyl ester
CAS_number = 1617-90-9
ATC_prefix = C04
ATC_suffix = AX07
PubChem = 15376
DrugBank =
C=21 | H=26 | N=2 | O=3
molecular_weight = 354.44 g/mol
bioavailability =
metabolism =
elimination_half-life =
excretion =
pregnancy_category =
legal_status =
routes_of_administration =Vincamine is a peripheral
vasodilator that increases blood flow to the brain. It is anindole alkaloid (specifically atryptamine ) found in the leaves of "Vinca minor ", comprising about 25-65% of the indole alkaloids found in "Vinca minor" by weight. It is also found in the species "Catharanthus roseus ".Ref|Cook It can be synthesized from related alkaloids.Ref|UllmannVincamine is often used as a
nootropic agent to combat the effects of aging, or in conjunction with other nootropics (such aspiracetam ) for a variety of purposes.References
#Note|Cookcite journal
author = Cook, P; James, I
title = Cerebral vasodilators
journal = N Engl J Med.
volume = 305
issue = 26
pages = 1560–1564
date = Dec. 24, 1981
pmid = 7031468
#Note|Ullmanncite encyclopedia
title = Indole Alkaloids
encyclopedia = Ullmann's Encyclopedia of Industrial Chemistry, Fifth Edition
volume =
pages = 393
publisher = Wiley-VCH
date = 1985
id = ISBN: 3-527-20100-9
accessdate =External links
* [http://www.mpbio.com/includes/msds/ansi/en/158295-en-ansi.pdf Vincamine MSDS]
* [http://ntp-server.niehs.nih.gov/ntp/htdocs/Chem_Background/ExSumPdf/Vincamine.pdf Vincamine article at NIH.gov]ee also
*
Vinpocetine
Wikimedia Foundation. 2010.
