- Islet cell carcinoma
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Islet cell carcinoma Classification and external resources
A symptomatic patient with pheochromocytoma and islet cell tumor of the pancreas. A small right pheochromocytoma with a necrotic center (P) is seen. In addition, an intensely enhancing mass is present in the neck of the pancreas (I). Two small pancreatic cysts are also seen but the bulk of the pancreas is spared.ICD-O: M8150/3 MeSH D018273 Islet cell carcinoma or nesidioblastoma is an uncommon cancer of the endocrine pancreas.
It accounts for approximately 1.3% of pancreatic cancer.[1]
The term "nesidioblastoma" dates to at least 1938.[2]
Survival
Survival in islet cell carcinoma is highly dependent upon the degree of disease involvement; surgical cure is possible if the tumor is resected completely. Review articles using the Surveillance Epidemiology and End Results (SEER) national database have shown a median survival of about a decade for localized disease, six years for regional (confined to the region of the pancreas) and two years for those with distant disease.[3]
See also
References
- ^ Yao JC, Eisner MP, Leary C, et al. (Dec 2007). "Population-based study of islet cell carcinoma". Ann. Surg. Oncol. 14 (12): 3492–500. doi:10.1245/s10434-007-9566-6. PMC 2077912. PMID 17896148. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=2077912.
- ^ Laidlaw GF (1938). "Nesidioblastoma, the islet tumor of the pancreas". Am J Pathol. 14 (2): 125–34. PMC 1964945. PMID 19970380. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=1964945.
- ^ American Society of Clinical Oncology.
Tumors: digestive system neoplasia (C15–C26/D12–D13, 150–159/211) GI tract Upper GI tractGastric carcinoma · Signet ring cell carcinoma · Gastric lymphoma (MALT lymphoma) · Linitis plasticaUpper and/or lowerAccessory exocrine pancreas: Adenocarcinoma · Pancreatic ductal carcinoma
cystic neoplasms: Serous microcystic adenoma · Intraductal papillary mucinous neoplasm · Mucinous cystic neoplasm · Solid pseudopapillary neoplasm
PancreatoblastomaPeritoneum Tumors: endocrine gland neoplasia (C73–C75/D34–D35, 193–194/226–227) Pancreas/
islets of Langerhansneuroendocrine tumors/islet cell carcinoma: α:Glucagonoma · β:Insulinoma · δ:Somatostatinoma · G:Gastrinoma · VIPomaHypothalamic/
pituitary axes
+parathyroidPituitaryThyroidThyroid cancer (malignant): epithelial cell /carcinoma (Papillary, Follicular/Hurthle cell) · parafollicular cell (Medullary) · AnaplasticBenign: Thyroid adenoma · Struma ovariiParathyroidGonadssee genital neoplasiaPinealoma Pinealoblastoma · PineocytomaMEN This article about a neoplasm is a stub. You can help Wikipedia by expanding it.