Cathine


Cathine
Cathine
Systematic (IUPAC) name
(1S,2S)-2-amino-1-phenylpropan-1-ol
Clinical data
Pregnancy cat.  ?
Legal status  ?
Routes Oral
Pharmacokinetic data
Half-life 3 hours
Identifiers
CAS number 492-39-7 YesY
ATC code A08AA07
PubChem CID 441457
DrugBank DB01486
ChemSpider 390189 YesY
UNII E1L4ZW2F8O YesY
Chemical data
Formula C9H13NO 
Mol. mass 151.206 g/mol
SMILES eMolecules & PubChem
 YesY(what is this?)  (verify)

Cathine, also known as d-norpseudoephedrine, is a psychoactive drug of the phenethylamine and amphetamine chemical classes which acts as a stimulant. Along with cathinone, it is found naturally in Catha edulis (khat), and contributes to its overall effects.

Contents

Pharmacology

Like amphetamines, cathinone, and ephedrine, cathine acts as a releasing agent of norepinephrine and epinephrine, or as a norepinephrine releasing agent (NRA). It also acts as a dopamine releasing agent (DRA) to a lesser extent.

Chemistry

Cathine is one of the optical isomers of phenylpropanolamine (PPA).

Regulation

The World Anti-Doping Agency's list of prohibited substances (used for the Olympic Games among other athletic events) bars cathine in concentrations of over 5 micrograms per milliliter in urine. Cathine is a Schedule III drug under the Convention on Psychotropic Substances.[1] In the United States, it is classified as a Schedule IV controlled substance.

Cathine is found in shrub Catha edulis.

In Hong Kong, cathine is regulated under Schedule 1 of Hong Kong's Chapter 134 Dangerous Drugs Ordinance. Unlawful possession is punishable by severe fines and imprisonment.

See also

References


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