- Free nerve ending
A free nerve ending (FNE) is an unspecialized,
afferent nerveending, meaning it brings information from the body's periphery to the brain. They function as cutaneous receptorsand are essentially used by vertebratesto detect pain.
nerve endings are unencapsulated and have no complex sensory structures, unlike those found in Meissner's or Pacinian corpuscles. They are the most common type of nerveending, and are most frequently found in the skin. They penetrate the epidermis and end in the stratum granulosum.
Free nerve ending have different rate of adaptation,
stimulus modalitiesand fiber types.
Rate of adaption
Different types of FNE can be
rapidly adapting, intermediate adapting, or slowly adapting. Aδ fibres are fast-adapting, while C fibers are slowly adapting.
Free nerve endings can detect temperature, mechanical stimuli (touch, pressure, stretch) or pain (
nociception). Thus, different free nerve endings work as thermoreceptors, cutaneous mechanoreceptorsand nociceptors. In other words, they express polymodality.
The majority of Aδ (A delta) fibers (group III) and C (group IV) fibers end as free nerve endings.
* [http://www-medlib.med.utah.edu/pain_center/education/outlines/noci_transduc.html Nociception: Transduction] . From the University of Utah.
*" [http://www.mfi.ku.dk/ppaulev/chapter3/kap.3.htm Textbook in Medical Physiology And Pathophysiology: Essentials and clinical problems.] " Copenhagen Medical Publishers. 1999 - 2000
* [http://faculty.ncwc.edu/ddaley/B232%20Somatosensory%20sys.htm Somatosensory System] from Dr. Daley of North Carolina Wesleyan College.
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Look at other dictionaries:
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nerve end — noun the terminal structure of an axon that does not end at a synapse • Syn: ↑nerve ending • Hypernyms: ↑end, ↑terminal • Hyponyms: ↑free nerve ending, ↑Pacinian corpuscle, ↑propr … Useful english dictionary