Zolazepam


Zolazepam

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IUPAC_name = 6-(2-fluorophenyl)-2,8,10-trimethyl -2,5,9,10-tetrazabicyclo [5.3.0] deca-5,8,11-trien-3-one



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CAS_number = 31352-82-6
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PubChem = 35775
DrugBank =
C=15 | H=15|F=1|N=4|O=1
molecular_weight = 286.304
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Zolazepam (Flupyrazapon) is a pyrazolodiazepinone derivative structurally related to the benzodiazepine drugs, which is used as an anaesthetic for a wide range of animals in veterinary medicine. Zolazepam is usually administered in combination with other drugs such as the NMDA antagonist Tiletamine or the alpha-2 adrenergic receptor agonist Xylazine, depending on what purpose it is being used for.

Zolazepam, in combination with Tiletamine, has been used in the tranquilization of wild animals, such as gorillas and polar bears, and has been found to be in terms of reduced side-effects superior to ketamine. [cite journal |author= Sleeman JM |coauthors= Cameron K, Mudakikwa AB, Nizeyi JB, Anderson S, Cooper JE, Richardson HM, Macfie EJ, Hastings B, Foster JW. |journal = Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians. |title=Field anesthesia of free-living mountain gorillas (Gorilla gorilla beringei) from the Virunga Volcano region, Central Africa. |volume=31 |issue=1 |pages=9-14 |month=Mar |year=2000 |pmid=10884117] [cite journal |author= Cattet MR |coauthors= Caulkett NA, Polischuk SC, Ramsay MA. |journal = Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians. |title=Anesthesia of polar bears (Ursus maritimus) with zolazepam-tiletamine, medetomidine-ketamine, and medetomidine-zolazepam-tiletamine. |volume=30 |issue=3 |pages=354-60 |month=Sep |year=1999 |pmid=10572857]

References


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Look at other dictionaries:

  • zolazepam — noun A pyrazolodiazepinone derivative structurally related to the benzodiazepine drugs, used as an anaesthetic and tranquillizer for a wide range of animals …   Wiktionary

  • zolazepam hydrochloride — zo·la·ze·pam hy·dro·chlo·ride (zoґla zə pam) [USP] a sedative hypnotic compound used in veterinary practice in combination with tiletamine hydrochloride …   Medical dictionary

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