Coproporphyrinogen III

Coproporphyrinogen III
Coproporphyrinogen III
Identifiers
CAS number 2624-63-7
PubChem 321
MeSH Coproporphyrinogen+III
Properties
Molecular formula C36H44N4O8
Molar mass 660.757 g/mol
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Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
Infobox references

In the metabolism of porphyrin, the enzyme uroporphyrinogen III decarboxylase generates coproporphyrinogen III from uroporphyrinogen III, and coproporphyrinogen III oxidase converts it into protoporphyrinogen IX.


Heme synthesis—note that some reactions occur in the cytoplasm and some in the mitochondrion (yellow)
v · d · eTypes of tetrapyrroles
Bilanes
(Linear)
Phytobilins
Phytochromobilin
Phycobilins
Phycoerythrobilin · Phycocyanobilin · Phycourobilin · Phycoviolobilin
Macrocycle
Methylcobalamin · Adenosylcobalamin · Cyanocobalamin
Protoporphyrin IX · Heme (b, c, a, o) · Zinc protoporphyrin · Magnesium protoporphyrin
Phytoporphyrins
Reduced
porphyrins
Porphyrinogens
Chlorophyllide (Chlorophyll (a, b) · Phaeophytin (Bacteriochlorins
Isobacteriochlorins
Siroheme · Sirohydrochlorin
Corphins
biochemical families: prot · nucl · carb (glpr, alco, glys) · lipd (fata/i, phld, strd, gllp, eico) · amac/i · ncbs/i · ttpy/i
v · Heme metabolic intermediates
Porphyrin biosynthesis

early mitochondrial: D-Aminolevulinic acid

cytosolic: Porphobilinogen · Hydroxymethylbilane · Uroporphyrinogen III · Coproporphyrinogen III

late mitochondrial: Protoporphyrinogen IX · Protoporphyrin IX
Heme degradation
and excretion
Breakdown of heme
Intestine, excretion in feces
Kidney, excretion in urine

M: MET

mt, k, c/g/r/p/y/i, f/h/s/l/o/e, a/u, n, m

k, cgrp/y/i, f/h/s/l/o/e, au, n, m, epon

m(A16/C10),i(k, c/g/r/p/y/i, f/h/s/o/e, a/u, n, m)

M: MYL

cell/phys (coag, heme, immu, gran), csfs

rbmg/mogr/tumr/hist, sysi/epon, btst

drug (B1/2/3+5+6), btst, trns
biochemical families: prot · nucl · carb (glpr, alco, glys) · lipd (fata/i, phld, strd, gllp, eico) · amac/i · ncbs/i · ttpy/i



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