- Emde degradation
The Emde degradation (also called Emde-reaction or Emde-reduction) is a method for the reduction of a
quaternary ammonium cationto a tertiary aminewith sodium amalgam[ H. Emde. "Ber deutsch chem Ges" 42 (1909) p2590] [ W Pötsch. "Lexikon bedeutender Chemiker" (VEB Bibliographisches Institut Leipzig, 1989) (ISBN 3817110553 ] [ M B Smith, J March. "March's Advanced Organic Chemistry" (Wiley, 2001) (ISBN 0-471-58589-0)]
organic reactionwas first described in 1909 by the German chemist Hermann Emde and was for a long time of great importance in structure elucidation of many alkaloids, for example that of ephedrine.
reducing agents exist for this reaction; for instance, lithium aluminium hydride.
* Related reactions are the
Hofmann eliminationand the Von Braun reaction
Wikimedia Foundation. 2010.
См. также в других словарях:
List of organic reactions — Well known reactions and reagents in organic chemistry include Contents: A B C D E F G H I J K L M N O P Q R S T U V W X Y Z See also Ext … Wikipedia
Amine — For other uses, see Amine (disambiguation). Primary amine Secondary amine Tertiary amine … Wikipedia
Hofmann elimination — (also known as exhaustive methylation ) is a process where an amine is reacted to create a tertiary amine and an alkene by treatment with excess methyl iodide followed by treatment with silver oxide, water, and heat [JerryMarch] . :After the… … Wikipedia
Sodium amalgam — Sodium amalgam, commonly denoted Na(Hg), is an amalgam, or alloy of mercury, with sodium metal. When metallic sodium is dissolved in mercury, it reacts exothermically to produce the intermetallic compound NaHg2, with enough heat to cause… … Wikipedia
Scientific phenomena named after people — This is a list of scientific phenomena and concepts named after people (eponymous phenomena). For other lists of eponyms, see eponym. NOTOC A* Abderhalden ninhydrin reaction Emil Abderhalden * Abney effect, Abney s law of additivity William de… … Wikipedia