Nodular fasciitis

Nodular fasciitis
Nodular fasciitis
Classification and external resources

Micrograph of nodular fasciitis showing the haphazard arrangement of cells (tissue culture-like pattern). H&E stain.
ICD-10 M72.4
ICD-9 728.79

Nodular fasciitis (also known as "Nodular pseudosarcomatous fasciits,"[1] "Pseudosarcomatous fasciitis,"[2], and "Subcutaneous pseudosarcomatous fibromatosis"[1]:992) is a benign[3] lesion most commonly found in the superficial fascia. It is most common in young persons on the upper extremities and trunk. Commonly mistaken for a sarcoma.

Contents

Etiology and clinical course

Similar to a dermatofibroma, it is believed to be a reparative process secondary to trauma, which is frequently not remembered. It evolves rapidly, but is usually less than 3 cm in diameter. There is an extremely low incidence of recurrence after resection.

Histology

  • Histologically vast array of patterns.
  • Short S-shaped fascicles, inflammation, accelerated mitotic index with normal mitoses.
  • Essentially spindle cell proliferation.
  • Stroma is rich in collagen and/or myxoid ground substance.

Additional images

See also

References

  1. ^ a b Freedberg, et al. (2003). Fitzpatrick's Dermatology in General Medicine. (6th ed.). McGraw-Hill. ISBN 0071380760.
  2. ^ Rapini, Ronald P.; Bolognia, Jean L.; Jorizzo, Joseph L. (2007). Dermatology: 2-Volume Set. St. Louis: Mosby. ISBN 1-4160-2999-0. 
  3. ^ Sailon AM, Cappuccino G, Hameed M, Fleegler EJ (2008). "Nodular fasciitis of the hand over the metacarpophalangeal joint: a case report". Eplasty 8: e38. PMC 2491338. PMID 18725954. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=2491338. 

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