Ecdysone


Ecdysone
Ecdysone
Identifiers
CAS number 3604-87-3 YesY
PubChem 19212
ChemSpider 18130 YesY
ChEBI CHEBI:16688 YesY
ChEMBL CHEMBL549300 YesY
Jmol-3D images Image 1
Properties
Molecular formula C27H44O6
Molar mass 464.63 g/mol
 YesY (verify) (what is: YesY/N?)
Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
Infobox references

Ecdysone is a steroidal prohormone of the major insect molting hormone 20-hydroxyecdysone, which is secreted from the prothoracic glands. Insect molting hormones (ecdysone and its homologues) are generally called ecdysteroids. Ecdysteroids act as moulting hormones of arthropods but also occur in other related phyla where they can play different roles. In Drosophila melanogaster, an increase in ecdysone concentration induces the expression of genes coding for proteins that the larva requires, and it causes chromosome puffs (sites of high expression) to form. Ecdysteroids also appear in many plants mostly as a protection agent (toxins or antifeedants) against herbivorous insects. These phytoecdysteroids have been reputed to have medicinal value and are part of herbal adaptogenic remedies like Cordyceps, yet an ecdyseroid precursor in plants has been shown to have cytotoxic properties [1]. A pesticide sold with the name MIMIC has ecdysteroid activity, although its chemical structure has little resemblance to the ecdysteroids.

See also

External links

  • Ecdybase, The Ecdysone Handbook - a free online ecdysteroids database

Notes

  1. ^ Wang YS, Yang JH, Luo SD, Zhang HB, Li L, Molecules. 2007;12(3):536-42



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  • ecdysone — [ ɛkdizɔn; ɛkdizon ] n. f. • 1955; all. Ecdyson, de Ecdysis « mue », gr. ekdusis « action de se dépouiller » ♦ Biol. Hormone produite par les glandes du prothorax des insectes, qui stimule la mue des larves. ● ecdysone nom féminin (grec ekdusis,… …   Encyclopédie Universelle

  • Ecdysone —   [griechisch], Singular Ecdyson das, s, Ekdysone, Steroidhormone, die bei Insekten und Krebsen die Häutungen der verschiedenen Entwicklungsstadien steuern. Das Ecdyson (α Ecdyson) wird bei Insekten in der …   Universal-Lexikon

  • ecdysone — [ek′də sōn΄] n. [ ECDYSIS + ONE] a hormone produced in the prothoracic glands of insects or in similar glands in crustaceans, for stimulating growth and the molting of the exoskeleton …   English World dictionary

  • Ecdysone — Formules de l ecdysone et de la 20 hydroxy ecdysone (en rouge, l hydroxyle supplémentaire sur le carbone 20) L ecdysone est une hormone stéroïde intervenant notamment dans le processus de la mue des arthropodes et dans le contrôle de leur… …   Wikipédia en Français

  • ecdysone — Family of steroid hormones found in insects, crustaceans and plants. In insects, a ecdysone stimulates moulting. The steadily maturing character of the moults is affected by steadily decreasing levels of juvenile hormone. b ecdysone (ecdysterone) …   Dictionary of molecular biology

  • ecdysone — also ecdyson noun Etymology: International Scientific Vocabulary ecdysis + hormone Date: 1956 any of several arthropod hormones that in insects are produced by the prothoracic gland and that trigger molting and metamorphosis …   New Collegiate Dictionary

  • ecdysone — n. [Gr. ekdysis, getting out of] (ARTHROPODA) A hormone that initates changes in cells associated with molting, produced by a secretion of the prothoracotrophic hormone from the median neurosecretory cells of insects, and the Ygland of… …   Dictionary of invertebrate zoology

  • ecdysone — /ek deuh zohn , sohn /, n. an insect hormone that stimulates metamorphosis. [1955 60; ECDYS(IS) + ONE] * * * …   Universalium

  • ecdysone — noun A hormone in insects and other arthropods that promotes molting. See Also: ecdysis …   Wiktionary

  • ecdysone — ec·dy·sone ek də .sōn also ec·dy·son .sän n any of several arthropod hormones that in insects are produced by the prothoracic gland and that trigger molting and metamorphosis * * * ec·dy·sone (ek diґson) [Gr. ekdysis a getting out] the hormone… …   Medical dictionary