Name = PAGENAME
ICD10 = ICD10|A|49|9|a|30 (NOS)
ICD9 = ICD9|790.7
MeshID = D016470
Bacteremia (Bacteræmia in British English) is the presence of bacteria in the
blood. The blood is normally a sterile environment, so the detection of bacteria in the blood (most commonly with blood cultures) is always abnormal.
Bacteria can enter the bloodstream as a severe complication of
infections (like pneumoniaor meningitis), during surgery (especially when involving mucous membranessuch as the gastrointestinal tract), or due to cathetersand other foreign bodiesentering the arteriesor veins(including intravenous drug abuse).
Bacteremia can have several consequences. The
immune responseto the bacteria can cause sepsis(blood poisoning) and septic shock, which has a relatively high mortality rate. Bacteria can also use the blood to spread to other parts of the body (which is called hematogenousspread), causing infections away from the original site of infection. Examples include endocarditisor osteomyelitis. Treatment is with antibiotics, and prevention with antibiotic prophylaxis can be given in situations where problems are to be expected.
Bacteremia is the presence of viable bacteria in the blood stream.Bacteremia is different from
sepsis(so-called blood poisoning or toxemia), which is a condition where bacteremia is associated with an inflammatory response from the body (causing systemic inflammatory response syndrome, characterised by rapid breathing, low blood pressure, fever, etc.). For example, a dental procedure(or even brushing your teeth) introduces a detectable amount of bacteria into the bloodstream, but these are unable to replicate in the blood of most people. Some patients with prosthetic heart valveshowever need antibiotic prophylaxis for dental surgery because bacteremia might lead to endocarditis( infectionof the interior lining of the heart). Salmonella - which is assumed to only cause gastroenteritis in much of the middle-class or developed world - can cause a specific and virulent form of bacteremia in the developing world, especially in Africa. This form of bacteremia is particularly deadly to infants and people whose immune systems have been damaged by HIV, according to studies done by the Universities of Malawi and Liverpool at the Wellcome Trust Clinical Research Programme in Blantyre. Researchers announced in March 2008 in the Journal of Clinical Investigation that a study of 352 Malawian children had revealed antibodies against salmonella when the bacteria leaves the safety of the cells and moves into the bloodstream, and these antibodies may form the basis of an eventual vaccine. Septicemiais an ill-defined non-scientific term introducing more confusion between sepsis and bacteremia: it suggests there is something in the bloodstream causing sepsis.
In the hospital, indwelling
catheters are a frequent cause of bacteremia and subsequent nosocomialinfections, because they provide a means by which bacteria normally found on the skin can enter the bloodstream. Other causes of bacteremia include dental procedures (occasionally including simple tooth brushing), herpes(including herpetic whitlow), urinary tract infections, intravenous drug use, and colorectal cancer. Bacteremia may also be seen in oropharyngeal, gastrointestinalor genitourinary surgeryor exploration.
Bacteremia, as noted above, frequently elicits a vigorous immune system response. The constellation of findings related to this response (such as
fever, chills, or hypotension) is referred to as sepsis. In the setting of more severe disturbances of temperature, respiration, heart rate or white blood cellcount, the response is characterized as septic shock, and may result in " multiple organ dysfunction syndrome".
Bacteremia is the principal means by which local
infections are spread to distant organs (referred to as "hematogenous spread"). Bacteremia is typically transient rather than continuous, due to a vigorous immune systemresponse when bacteria are detected in the blood. Hematogenous dissemination of bacteria is part of the pathophysiology of meningitisand endocarditis, and of Pott's diseaseand many other forms of osteomyelitis.
Bacteremia is most commonly diagnosed by
blood culture, in which a sample of blood is allowed to incubate with a medium that promotes bacterial growth. Since blood is normally sterile, this process does not normally lead to the isolation of bacteria. If, however, bacteria are present in the bloodstream at the time the sample is obtained, the bacteria will multiply and can thereby be detected. Any bacteria that incidentally find their way to the culture medium will also multiply. For this reason, blood cultures must be drawn with great attention to sterile process. Occasionally, blood cultures will reveal the presence of bacteria that represent contamination from the skinthrough which the culture was obtained. Blood cultures must be repeated at intervals to determine if persistent — rather than transient — bacteremia is present.
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Bacteremia — Saltar a navegación, búsqueda Bacteriemia (bacteremia) es la presencia de bacterias en la sangre. La sangre es normalmente un ambiente estéril, por lo tanto la detección de una bacteria en la sangre (sobre todo con un hemocultivo) es siempre… … Wikipedia Español
bacteremia — ac ter*e mi*a (b[a^]k*t[=e]r*[=e] m[=e]*[.a] or b[a^]k t[u^]*r[=e] m[=e]*[.a]), n. The presence of bacteria in the blood. Syn: bacteriemia. [WordNet 1.5] … The Collaborative International Dictionary of English
bacteremia — [bak΄tə rē′mē ə] n. [ BACTER(IA) + EMIA] the presence of bacteria in the bloodstream … English World dictionary
bacteremia — /bak teuh ree mee euh/, n. Pathol. the presence of bacteria in the blood. [1885 90; BACTER + EMIA] * * * Presence of bacteria in the blood. Short term bacteremia follows dental or surgical procedures, especially if local infection or very high… … Universalium
Bacteremia — The presence of live bacteria in the bloodstream. Bacteremia is analogous to viremia (the presence of a virus in the blood) and parasitemia (the presence of a parasite in the blood). Bacteremia, viremia and parasitemia are all forms of sepsis… … Medical dictionary
bacteremia — noun Etymology: New Latin, alteration of bacteriemia, from bacteri + emia Date: circa 1890 the usually transient presence of bacteria in the blood • bacteremic adjective … New Collegiate Dictionary
bacteremia — n. [Gr. bakterion, small rod; haima, blood] The presence of bacteria in the hemolymph or blood of invertebrates, without production of harmful toxins or other deleterious effects … Dictionary of invertebrate zoology
bacteremia — (bak ter e me ah) The presence of viable bacteria in the blood … Dictionary of microbiology
bacteremia — n. bacteria in the blood (Medicine) … English contemporary dictionary
bacteremia — bac·te·re·mia … English syllables