Hyperpituitarism is the result of excess secretion of adenohypophyseal trophic hormones most commonly by a functional pituitary adenoma. Other causes are hyperplasias and carcinomas of the adenohypophysis, secretion by non-pituitary tumours and certain hypothalamic disorders.

Clinical manifestations

Depending on the cell type(s) affected, clinical manifestations of hormone excess may include:
*Cushing's disease
*Precocious puberty
*Gigantism or Acromegaly
*Hyperthyroidism (rare)

Associated conditions

When there is an enlargement of the pituitary tissue, hyperpituitarism is often associated with:
*Visual field defects, classically bitemporal hemianopia
*Radiographic abnormalities of the sella turcica, such as sellar expansion, bony erosion and disuption of the diaphragma sellae
*Increased intracranial pressure


Symptoms caused by hormone excess and associated mass effects include:
* Headache
* Visual field loss or Double vision
* Excessive sweating
* Hoarseness
* Milk secretion from breast
* Sleep apnea
* Carpal tunnel syndrome
* Joint pain and limitation of motion
* Muscle weakness
* Numbness or tingling of skin

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  • hyperpituitarism — [hī΄pərpi to͞o′i tə riz΄əm, hī΄pər pityo͞o′i tə riz΄əm] n. 1. excessive activity of the pituitary gland, esp. of its anterior lobe 2. a condition resulting from this, as gigantism hyperpituitary [hī΄pər pi to͞o′iter΄ē, hī΄pər pi tyo͞o′iter΄ē] adj …   English World dictionary

  • hyperpituitarism — noun excessive activity of the pituitary gland (especially overactivity of the anterior lobe which leads to excess secretion of growth hormone) • Hypernyms: ↑glandular disease, ↑gland disease, ↑glandular disorder, ↑adenosis • Part Holonyms:… …   Useful english dictionary

  • hyperpituitarism — noun Etymology: International Scientific Vocabulary Date: 1909 excessive production of growth hormones by the pituitary gland • hyperpituitary adjective …   New Collegiate Dictionary

  • hyperpituitarism — /huy peuhr pi tooh i teuh riz euhm, tyooh /, n. Pathol. 1. overactivity of the pituitary gland. 2. a resultant condition, as giantism or acromegaly. [1905 10; HYPER + PITUITAR(Y) + ISM] * * * …   Universalium

  • hyperpituitarism — noun The condition caused by excessive secretion of hormones by pituitary tumors …   Wiktionary

  • hyperpituitarism — Excessive production of anterior pituitary hormones, especially growth hormone; may result in gigantism or acromegaly. * * * hy·per·pi·tu·ita·rism pə t(y)ü ət ə .riz əm, t(y)ü ə .triz n excessive production of growth hormones by the pituitary… …   Medical dictionary

  • hyperpituitarism — n. excessive activity of the pituitary gland …   English contemporary dictionary

  • hyperpituitarism — hy·per·pi·tu·i·ta·rism …   English syllables

  • hyperpituitarism — hy•per•pi•tu•i•ta•rism [[t]ˌhaɪ pər pɪˈtu ɪ təˌrɪz əm, ˈtyu [/t]] n. 1) pat overactivity of the pituitary gland 2) pat a resultant condition, as gigantism or acromegaly • Etymology: 1905–10 …   From formal English to slang

  • hyperpituitarism — /haɪpəpɪˈtjuətərɪzəm/ (say huypuhpi tyoohuhtuhrizuhm) noun 1. overactivity of the pituitary gland. 2. the resultant condition, as gigantism or acromegaly …   Australian English dictionary

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