Ghon focus


Ghon focus

A Ghon focus is a primary lesion caused by mycobacterium bacilli (tuberculosis) developed in the lung of a previously uninfected individual. It is named for Anton Ghon (1866-1936), an Austrian pathologist.

It is a small area of granulomatous inflammation, only detectable by chest X-ray if it calcifies or grows substantially (see tuberculosis radiology) Kumar, Vinay; Abbas, Abul K.; Fausto, Nelson; & Mitchell, Richard N. (2007). "Robbins Basic Pathology" (8th ed.). Saunders Elsevier. pp. 516-522 ISBN 978-1-4160-2973-1] . Typically these will heal, but in some cases, especially in immunosuppressed patients, it will progress to miliary tuberculosis (so named due to the calcified granulomas resembling millet seeds on a chest X-ray).

The classical location for primary infection is surrounding the lobar fissures, either in the upper part of the lower lobe or lower part of the upper lobe.

If the Ghon focus also involves infection of surrounding lymph nodes, it is known as the Ghon's complex or primary complex [http://www.smbs.buffalo.edu/pth600/IMC-Path/y2case/y2ans10.htm] .

References


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Look at other dictionaries:

  • Ghon focus — the primary parenchymal lesion of primary pulmonary tuberculosis; when associated with a corresponding lymph node focus, it is known as the primary or Ghon complex. Called also Ghon primary lesion and Ghon tubercle. Ghon focus (arrow) in… …   Medical dictionary

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  • Ghon's focus — the lesion produced in the lung of a previously uninfected person by tubercle bacilli. It is a small focus of granulomatous inflammation, which may become visible on a chest X ray if it grows large enough or if it calcifies. A Ghon focus usually… …   Medical dictionary

  • Ghon's focus — the lesion produced in the lung of a previously uninfected person by tubercle bacilli. It is a small focus of granulomatous inflammation, which may become visible on a chest X ray if it grows large enough or if it calcifies. A Ghon focus usually… …   The new mediacal dictionary

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