Klüver-Bucy syndrome


Klüver-Bucy syndrome

DiseaseDisorder infobox
Name = Klüver-Bucy syndrome
ICD10 = ICD10|F|07|0|f|00
ICD9 = ICD9|310.0

Klüver-Bucy syndrome is a behavioral disorder that occurs when both the right and left medial temporal lobes of the brain malfunction. The amygdala has been a particularly implicated brain region in the pathogenesis of this syndrome.

In rhesus monkeys

The syndrome is named for Heinrich Klüver and Paul Bucy, who removed the temporal lobe bilaterally in rhesus monkeys in an attempt to determine its function. This caused the monkeys to develop visual agnosia, emotional changes, altered sexual behavior, hypermetamorphosis and oral tendencies.

Though the monkeys could see, they were unable to recognize even previously familiar objects, or their use. They would examine their world with their mouths instead of their eyes ("oral tendencies") and developed a desire to explore everything ("hypermetamorphosis").

The monkeys indulged in indiscriminate sexual behavior including masturbation, heterosexual acts and homosexual acts. Contrary to popular belief, however, the findings did not show an increase in sexual behavior ("hypersexualism").

Emotionally, the monkeys became dulled, and their facial expressions and vocalizations became far less expressive. They were also less fearful of things that would have instinctively panicked them in their natural state, such as humans or snakes. Even after being attacked by a snake, they would willingly approach it again. This aspect of change was termed "placidity".

In humans

People with lesions in their temporal lobes (a bilateral lesion) show similar behaviors. They may display oral or tactile exploratory behavior (socially inappropriate licking or touching); hypersexuality; bulimia; memory disorders; flattened emotions (placidity); and an inability to recognize objects or inability to recognize faces.

The full syndrome rarely, if ever, develops in humans. However, parts of it are often noted in patients with extensive bilateral temporal damage caused by herpes or other encephalitis, dementias of degenerative (Alzheimer's disease, Pick's Disease) or post-traumatic etiologies or cerebrovascular disease.

External links

* [http://www.ninds.nih.gov/disorders/kluver_bucy/kluver_bucy.htm The National Institute of Neurological Disorders and Stroke - Kluver-Bucy Syndrome]
* [http://neuro.psychiatryonline.org/cgi/content/full/11/1/116 Anatomic Basis of Klüver-Bucy Syndrome]
* [http://cogprints.org/2872/ Monkeys With Amygdala Lesions]
* [http://www.neurologyindia.com/article.asp?issn=0028-3886;year=2004;volume=52;issue=3;spage=369;epage=371;aulast=Jha Six distinct case studies of KBS in India]


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  • Kluver-Bucy syndrome — Klü·ver Bu·cy syndrome klü vər b(y)ü sē , klev ər , klue vər n a group of symptoms that are caused by bilateral removal of the temporal lobes, that include excessive reactivity to visual stimuli, hypersexuality, diminished emotional responses,… …   Medical dictionary

  • Klüver-Bucy syndrome — /klooh veuhr byooh see/, Psychiatry. a syndrome caused by bilateral injury to the temporal lobes and characterized by memory defect, hypersexuality, excessive oral behavior, and diminished fear reactions. [after German born U.S. neurologist… …   Universalium

  • Klüver-Bucy syndrome — /klooh veuhr byooh see/, Psychiatry. a syndrome caused by bilateral injury to the temporal lobes and characterized by memory defect, hypersexuality, excessive oral behavior, and diminished fear reactions. [after German born U.S. neurologist… …   Useful english dictionary

  • Syndrome de Kluver & Bucy — Syndrome de Klüver Bucy Syndrome de Klüver Bucy CIM 10 : F07.0 Le syndrome de Klüver Bucy a été découvert par le psychologue Heinrich Klüver et le neurochirurgien Paul Bucy de l université de Chicago. Le syndrome de Klüver et Bucy a été… …   Wikipédia en Français

  • Syndrome de Klüver & Bucy — Syndrome de Klüver Bucy Syndrome de Klüver Bucy CIM 10 : F07.0 Le syndrome de Klüver Bucy a été découvert par le psychologue Heinrich Klüver et le neurochirurgien Paul Bucy de l université de Chicago. Le syndrome de Klüver et Bucy a été… …   Wikipédia en Français

  • Syndrome de klüver & bucy — Syndrome de Klüver Bucy Syndrome de Klüver Bucy CIM 10 : F07.0 Le syndrome de Klüver Bucy a été découvert par le psychologue Heinrich Klüver et le neurochirurgien Paul Bucy de l université de Chicago. Le syndrome de Klüver et Bucy a été… …   Wikipédia en Français

  • Syndrome de Klüver & Bucy — Pour les articles homonymes, voir Bucy. Classification internationale des maladies CIM 10 : F07.0 Le syndrome de Klüver Bucy a été découvert par le …   Wikipédia en Français

  • Síndrome de Klüver-Bucy — Clasificación y recursos externos CIE 10 F07.0 CIE 9 310.0 DiseasesDB …   Wikipedia Español

  • Bucy — Le terme Bucy peut faire référence à : Sommaire 1 Toponymie 2 Hydrographie 3 Patronyme 4 Autres 5 Voir aussi …   Wikipédia en Français

  • Klüver, Heinrich — ▪ American psychologist and neurologist born May 25, 1897, Holstein, Ger. died Feb. 8, 1979, Oak Lawn, Ill., U.S.       German born U.S. experimental psychologist (experimental psychology) and neurologist (neurology) who made many contributions… …   Universalium