Prolactin receptor

Prolactin receptor

protein
Name=prolactin receptor
caption=


width=
HGNCid=9446
Symbol=PRLR
AltSymbols=
EntrezGene=5618
OMIM=176761
RefSeq=NM_000949
UniProt=P16471
PDB=
ECnumber=
Chromosome=5
Arm=p
Band=13
LocusSupplementaryData=-p12
The prolactin receptor—encoded by a gene on Chromosome 5p13-14—interacts with the prolactin molecule as a transmembrane receptor.

Thus it contains an extracellular region that binds prolactin, a transmembrane regions, and a cytoplasmatic region.

The receptor is a cytokine receptor, and the second messenger cascade is the JAK-STAT pathway.

There may be variations among different tissue prolactin receptors.

ee also

*Prolactin-releasing peptide receptor
*PREB
*PRLH

External links

*


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