Yersinia pseudotuberculosis

Taxobox
color = lightgrey
name = "Yersinia pseudotuberculosis"
regnum = Bacteria
phylum = Proteobacteria
classis = Gammaproteobacteria
ordo = Enterobacteriales
familia = Enterobacteriaceae
genus = "Yersinia"
species = "Y. pseudotuberculosis"
binomial = "Yersinia pseudotuberculosis"
binomial_authority = (Pfeiffer 1889)
Smith & Thal 1965

"Yersinia pseudotuberculosis" is a Gram-negative bacterium which primarily causes disease in animals; humans occasionally get infected zoonotically, most often through the food-borne route.cite book | author = Ryan KJ; Ray CG (editors) | title = Sherris Medical Microbiology | edition = 4th ed. | publisher = McGraw Hill | year = 2004 | id = ISBN 0-8385-8529-9 ]

Pathogenesis

In animals, "Y. pseudotuberculosis" can cause tuberculosis-like symptoms, including localized tissue necrosis and granulomas in the spleen, liver, and lymph node.

In humans, symptoms are similar to those of infection with "Y. enterocolitica" (fever and right-sided abdominal pain), except that the diarrheal component is often absent, which sometimes makes the resulting condition difficult to diagnose. "Y. pseudotuberculosis" infections can mimic appendicitis, especially in children and younger adults, and, in rare cases the disease may cause skin complaints (erythema nodosum), joint stiffness and pain (reactive arthritis), or spread of bacteria to the blood (bacteremia).

Infection usually becomes apparent 5–10 days after exposure and typically lasts 1–3 weeks without treatment. In complex cases or those involving immunocompromised patients, antibiotics may be necessary for resolution; ampicillin, aminoglycosides, tetracycline, chloramphenicol, or a cephalosporin may all be effective.

The recently described syndrome "Izumi-fever" has been linked to infection with "Y.pseudotuberculosis". [cite web | author=Jani, Asim| year=2003| title=Pseudotuberculosis (Yersina) | work= | url=http://www.emedicine.com/med/topic1947.htm | accessdate=2006-03-04]

References

External links

* [http://cmr.tigr.org/tigr-scripts/CMR/GenomePage.cgi?org=ntyp05 Yersinia pseudotuberculosis genome]