:For|financial immunization|Immunization (finance)
Immunization, or immunisation, is the process by which an individual's
immune systembecomes fortified against an agent (known as the immunogen).
When an immune system is exposed to
molecules that are foreign to the body ("non-self"), it will orchestrate an immune response, but it can also develop the ability to quickly respond to a subsequent encounter (through immunological memory). This is a function of the adaptive immune system. Therefore, by exposing an animal to an immunogen in a controlled way, their body can learn to protect itself: this is called active immunisation.
The most important elements of the immune system that are improved by immunisation are the
B cells (and the antibodies they produce) and T cells. Memory B celland memory T cellsare responsible for a swift response to a second encounter with a foreign molecule. Passive immunization is when these elements are introduced directly into the body, instead of when the body itself has to make these elements.
Immunisation can be done through various techniques, most commonly
vaccination. Vaccines against microorganisms that cause diseases can prepare the body's immune system, thus helping to fight or prevent an infection. The fact that mutations can cause cancercells to produce proteins or other molecules that are unknown to the body forms the theoretical basis for therapeutic cancer vaccines. Other molecules can be used for immunisation as well, for example in experimental vaccines against nicotine( NicVAX) or the hormone ghrelin(in experiments to create an obesity vaccine).
Passive and active immunization
Immunisation can be achieved in an active or passive fashion: vaccination is an active form of immunization.
Active immunisation entails the introduction of a foreign molecule into the body, which causes the body itself to generate immunity against the target. This immunity comes from the T cells and the B cells with their antibodies.
Active immunization can occur naturally when a person comes in contact with, for example, a microbe. If the person has not yet come into contact with the
microbeand has no pre-made antibodies for defense (like in passive immunization), the person can become immunized. The immune system will eventually create antibodies and other defenses against the microbe. The next time, the immune response against this microbe can be very efficient; this is the case in many of the childhood infections that a person only contracts once, but then is immune.
Artificial active immunization is where the microbe, or parts of it, are injected into the person before they are able to take it in naturally. If whole microbes are used, they are pre-treated, so that they will not harm the injected person as the naturally occurring microbe would. Depending on the type of disease, this technique also works with dead microbes, parts of the microbe, or treated
toxinsfrom the microbe.
Passive immunization is where pre-made elements of the immune system are transferred to a person, and the body doesn't have to create these elements itself. Currently,
antibodiescan be used for passive immunization. This method of immunization begins to work very quickly, but it is short lasting, because the antibodies are naturally broken down, and if there are no B cells to produce more antibodies, they will disappear.
Passive immunization can be naturally acquired when
antibodiesare being transferred from mother to fetusduring pregnancy, to help protect the foetus before and shortly after birth.
Artificial passive immunization is normally given by
injectionand is used if there has been a recent outbreak of a particular disease or as an emergency treatment to poisons (for example, for tetanus). The antibodies can be produced in animals or " in vitro".
* [http://www.immunizationinfo.org National Network for Immunization Information (NNii)]
* [http://www.cdc.gov/nip Centers for Disease Control National Immunization Program ]
Wikimedia Foundation. 2010.
Look at other dictionaries:
immunization — n. the act of making immune (especially by inoculation). Syn: immunisation. [WordNet 1.5] … The Collaborative International Dictionary of English
immunization — immunization. См. иммунизация. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) … Молекулярная биология и генетика. Толковый словарь.
immunization — index tolerance Burton s Legal Thesaurus. William C. Burton. 2006 … Law dictionary
immunization — (n.) 1893, from IMMUNIZE (Cf. immunize) + ATION (Cf. ation) … Etymology dictionary
immunization — (Amer.) imÂ·muÂ·niÂ·zaÂ·tion || â€šÉªmjÉ™nÉ™ zeÉªÊƒn / jÊŠnaÉª z n. process of rendering insusceptible to a disease (also immunisation) … English contemporary dictionary
immunization — /im yeuh neuh zay sheuhn, i myooh /, n. 1. the fact or process of becoming immune, as against a disease. 2. Finance. a method of protection against fluctuating bond interest rates by investing in securities having different yields and terms.… … Universalium
immunization — n. 1) to carry out a (mass) immunization against 2) active; passive immunization * * * [ˌɪmjʊnaɪ zeɪʃ(ə)n] passive immunization active to carry out a (mass) immunization against … Combinatory dictionary
Immunization — Vaccination. Immunizations work by stimulating the immune system, the natural disease fighting system of the body. The healthy immune system is able to recognize invading bacteria and viruses and produce substances (antibodies) to destroy or… … Medical dictionary
Immunization — A strategy that matches the durations of assets and liabilities thereby minimizing the impact of interest rates on the net worth. Also known as multiperiod immunization . For example, large banks must protect their current net worth, whereas… … Investment dictionary
immunization — noun a) The process by which an individual is exposed to a material that is designed to prime his or her immune system against that material. Immunization against influenza is important for all child care workers. b) One such exposure. The first… … Wiktionary