medicineand psychology, the term syndrome refers to the association of several clinically recognizable features, signs (observed by a physician), symptoms (reported by the patient), phenomena or characteristics that often occur together, so that the presence of one feature alerts the physicianto the presence of the others. In recent decades the term has been used outside of medicine to refer to a combination of phenomena seen in association.
In technical medical language, a syndrome refers only to the set of detectable characteristics. A specific
disease, condition, or 'disorder may be identified as the underlying cause. Once a physical cause has been identified, the word "syndrome" is sometimes kept in the name of the disease.
The term syndrome derives from the Greek and means literally "run together", as the features do. It is most often used when the reason that the features occur together (the
pathophysiologyof the syndrome) has not yet been discovered. A familiar syndrome name often continues to be used even after an underlying cause has been found, or when there are a number of different primary causes that all give rise to the same combination of symptoms and signs. Many syndromes are named after the physicians credited with first reporting the association; these are "eponymous" syndromes (see also the list of eponymous diseases, many of which are referred to as "syndromes"). Otherwise, disease features or presumed causes, as well as references to geography, historyor poetry, can lend their names to syndromes.
culture-bound syndromeis a set of symptoms where there is no evidence of an underlying biological cause, and which is only recognized as a "disease" in a particular culture.
yndromes and associated conditions
The description of a syndrome usually includes a number of "essential" characteristics, which when concurrent lead to the diagnosis of the condition. Frequently these are classified as a combination of typical major symptoms and signs - essential to the diagnosis - together with minor findings, some or all of which may be absent. A formal description may specify the minimum number of major and minor findings respectively, that are required for the diagnosis.
In contrast to the major and minor findings which are typical of the syndrome, there may be an association with other conditions, meaning that in persons with the specified syndrome these
associated conditionsoccur more frequently than would be expected by chance. While the syndrome and the associated conditions may be statistically related, they do not have a clear cause and effect relationship - i.e. there is likely to be a separate underlying problem or risk factorthat explains the association. An example would be Down syndromewhich has the associated condition of diabetes mellitus. A knowledge of associated conditions would dictate that they are specifically looked for in the management of the syndrome.
= Case studies = One recent
case studyis Acquired Immune Deficiency Syndrome (AIDS), so named because most syndromal immune deficiencies are either genetically precoded, or secondary to either metabolic disorders or hematological disease.
AIDS was originally termed "Gay Related Immune Disease" (or GRID), a name which was revised as the disease turned out to also affect heterosexuals. Several years passed after the recognition of AIDS before
HIV(human immunodeficiency virus) was first described, finally explaining the hitherto mysterious "syndrome".
SARS (severe acute respiratory syndrome) is an even more recent example of a syndrome that was later explained with the identification of a causative
* lists articles about specific medical syndromes.
* [http://www.whonamedit.com Whonamedit.com] - a repository of medical eponyms
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Look at other dictionaries:
Syndrôme — Syndrome Pour les articles homonymes, voir syndrome (homonymie). Un syndrome est un ensemble de signes cliniques et de symptômes qu un patient est susceptible de présenter lors de certaines maladies, ou bien dans des circonstances cliniques d… … Wikipédia en Français
syndrome — [ sɛ̃drom ] n. m. • 1824; n. f. de 1547 à 1872; gr. sundromê « réunion », par le lat. ♦ Méd. Association de plusieurs symptômes, signes ou anomalies constituant une entité clinique reconnaissable, soit par l uniformité de l association des… … Encyclopédie Universelle
Syndrome 4p — Syndrome de Wolf Hirschhorn Le syndrome de Wolf Hirschhorn est une maladie chromosomique associant : faciès caractéristique, retard de croissance intra utérin suivi d’un retard de croissance post natal, hypotonie musculaire, retard de… … Wikipédia en Français
syndrome — pronounced sin drohm, is originally a medical term for ‘a set of symptoms’. Its use as a vogue word in general contexts meaning ‘a characteristic combination of opinions, emotions, behaviour, etc.’, is as recent as the 1950s; it is generally… … Modern English usage
syndrome X — eks n 1) angina pectoris of a usu. benign form in which the coronary arteriogram is normal 2) metabolic syndrome * * * 1. cardiac s. X. 2. metabolic s … Medical dictionary
syndrome — a number of symptoms occurring together, 1540s, from Mod.L., from Gk. syndrome concurrence of symptoms, concourse, from syndromos, lit. running together, from syn with + dromos running, course (see DROMEDARY (Cf. dromedary)). Psychological sense… … Etymology dictionary
syndrome — [sin′drōm΄] n. [ModL < Gr syndromē < syn , with + dramein, to run: see DROMEDARY] 1. a number of symptoms occurring together and characterizing a specific disease or condition 2. any set of characteristics regarded as identifying a certain… … English World dictionary
Syndrome — Syn dro*me, n. [NL., from Gr. ?; sy n with + ? a course, a running.] 1. Concurrence. [R.] Glanvill. [1913 Webster] 2. (Med.) A group of symptoms occurring together that are characteristic and indicative of some underlying cause, such as a disease … The Collaborative International Dictionary of English
syndrome — syndrome. См. синдром. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) … Молекулярная биология и генетика. Толковый словарь.
Syndrŏme — (gr.), 1) das Zusammenwirken mehrer Umstände; 2) die Häufung vieler Krankheitsfälle … Pierer's Universal-Lexikon
Syndrome — Syndrome, griech., das Zusammenwirken mehrer Ursachen; Häufung der Krankheitsfälle … Herders Conversations-Lexikon