Erythroleukemia

Erythroleukemia

DiseaseDisorder infobox
Name = PAGENAME
ICD10 = ICD10|C|94|0|c|81
ICD9 = ICD9|207.0


Caption =
ICDO = ICDO|9840|3
OMIM = 133180
MedlinePlus =
eMedicineSubj = med
eMedicineTopic = 729
DiseasesDB =
MeshID = D004915

Erythroleukemia (or "acute Di Guglielmo syndrome") is a rare form of acute myeloid leukemia where the myeloproliferation is of erythrocyte precursors.

It is defined at type "M6" under the FAB classification.cite web |url=http://www.ucsfhealth.org/adult/medical_services/cancer/leukemia/conditions/aml/signs.html |title=Acute Myeloid Leukemia - Signs and Symptoms |format= |work=]

Types

It can be classified as follows:
* M6a; Erythroid/Myeloid

* M6b; Pure Erythroid Malignancy

Criteria for diagnosis of M6

M6a

50% or more of all nucleated bone marrow cells are erythroblasts, Dyserythropoiesis is prominent and 30% or more of the remaining cells (non- erythroid) are myeloblasts.

M6b ( Pure Erythroid Malignancy )

In rare cases the erythroid lineage is the only obvious components of an acute leukemia; a myeloblast component is not apparent. The erythroid component consists predominantly or exclusively of proerythroblasts and early basophilic erythroblasts. These cells may constitute 90% or more of the marrow elements. Despite this lack of myeloblast, these cases should be considered acute leukemias. In WHO proposal the blastic leukeimas that are limited to the erythroid series are designated pure erythroid malignancy.

References

External links

*
* [http://www.med-ed.virginia.edu/courses/path/innes/wcd/myeloid1.cfm Histology] at University of Virginia
* [http://www.academic.marist.edu/~jzmz/topics/erythroleukemia/myelomono1.html Overview] at Marist College
* [http://pathy.med.nagoya-u.ac.jp/atlas/doc/node48.html#SECTION00417000000000000000 Images] at Nagoya University


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См. также в других словарях:

  • Erythroleukemia — A form of acute myeloid leukemia (AML) involving the cells that give rise to the erythrocytes (the red blood cells). In this type of leukemia, the body produces large numbers of abnormal, immature red blood cells. Erythroleukemia is classified as …   Medical dictionary

  • erythroleukemia — noun erythroid leukemia …   Wiktionary

  • erythroleukemia — eryth·ro·leukemia …   English syllables

  • erythroleukemia — Cancer of the blood forming tissues in which large numbers of immature, abnormal red blood cells are found in the blood and bone marrow …   English dictionary of cancer terms

  • erythroleukemia — ə¦rithrōˌ noun Etymology: New Latin, from erythr + leukemia : a malignant disorder that is marked by proliferation of erythroblastic and myeloblastic tissue and in later stages by leukemia …   Useful english dictionary

  • acute erythroleukemia — a form of acute myelogenous leukemia representing erythroleukemia in which malignant precursors of leukocytes have proliferated and become predominant; called also Di Guglielmo syndrome …   Medical dictionary

  • erythremic myelosis — erythroleukemia …   Medical dictionary

  • Di Guglielmo syndrome — erythroleukemia …   Medical dictionary

  • M6 — erythroleukemia with dyserythropoiesis and megaloblastosis [Franco American British (FAB) classification] …   Medical dictionary

  • M6 — • erythroleukemia with dyserythropoiesis and megaloblastosis [Franco American British (FAB) classification] • band form in the 6th stage of myelocyte maturation …   Dictionary of medical acronyms & abbreviations


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