Imidazoline

Imidazoline
Imidazoline
Identifiers
CAS number 504-75-6 YesY
PubChem 68156
ChemSpider 61464 YesY
ChEBI CHEBI:53094 YesY
Jmol-3D images Image 1
Properties
Molecular formula C3H6N2
Molar mass 70.09 g mol−1
 YesY (verify) (what is: YesY/N?)
Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
Infobox references

Imidazoline is a nitrogen-containing heterocycle with formula C3H6N2, derived from imidazole. The ring contains an imine bond, and the carbons at the 4 and 5 positions are singly bonded, rather than doubly bonded for the case of imidazole. Imidazolines are structurally related to guanidines and amidines.

Chemical relationship of imidazole to its reduced derivatives.


Second generation Grubbs' catalyst

Like imidazole, imidazoline-based compounds have been used as N-heterocyclic carbene ligands on various transition metals. It is found in the commercially available second generation Grubbs' catalyst.

Biological role

Many imidazolines are biologically active.[1] Most bio-active derivatives bear a substituent (aryl or alkyl group) on the carbon between the nitrogen centers. Some generic names include oxymetazoline, xylometazoline, tetrahydrozoline, and naphazoline.

See also

References


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Look at other dictionaries:

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  • Imidazoline — sind eine chemische Stoffgruppe aus dem Bereich der heterocyclischen Verbindungen und gehören zur Gruppe der Azoline. Ihre Mitglieder sind fünfgliedrige cyclische organische ungesättigte Verbindungen, die genau zwei nicht benachbarte… …   Deutsch Wikipedia

  • imidazoline — imidazolinas statusas T sritis chemija apibrėžtis Heterociklinis junginys. formulė C₃H₆N₂ atitikmenys: angl. imidazoline rus. имидазолин ryšiai: sinonimas – dihidroimidazolas …   Chemijos terminų aiškinamasis žodynas

  • Imidazoline receptor — Imidazoline receptors are receptors for clonidine and other imidazolines.cite journal | author = Head GA, Mayorov DN | title = Imidazoline receptors, novel agents and therapeutic potential | journal = Cardiovasc Hematol Agents Med Chem | volume …   Wikipedia

  • imidazoline — noun A five membered heterocycle containing three carbon atoms, two non adjacent nitrogen atoms and one double bond …   Wiktionary

  • imidazoline — im·id·az·o·line .im ə daz ə .lēn n any of three dihydro derivatives C3H6N2 of imidazole with adrenergic blocking activity also a derivative of these …   Medical dictionary

  • imidazoline — im·id·az·o·line …   English syllables

  • imidazoline — ˌiməˈdazəˌlēn noun ( s) Etymology: imidazole + ine : any of three dihydro derivatives C3H6N2 of imidazole; also : a derivative of these called also glyoxalidine …   Useful english dictionary

  • imidazoline receptors — Receptors for imidazolines such as agmatine and idazoxan that modulate sympathetic outflow in the brainstem. I1 is elevated on platelets and in brains of patients with depression. Also expressed on vascular smooth muscle where they may mediate… …   Dictionary of molecular biology

  • idazoxan — Imidazoline alpha 2 adrenoreceptor antagonist, also binds to imidazoline receptors …   Dictionary of molecular biology

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