Potassium tert-butoxide

Potassium tert-butoxide

chembox new
ImageFile=Potassium tert-butoxide.pngImageSize=120px
IUPACName=potassium 2-methylpropan-2-olate
OtherNames=
Section1=Chembox Identifiers
CASNo=865-47-4
PubChem=23665647
SMILES=CC(C)(C) [O-] . [K+]
Section2=Chembox Properties
Formula=C4H9KO
MolarMass=112.21196
Appearance=
Density=
MeltingPtC=240
BoilingPtC=
Solubility=
Section3=Chembox Hazards
ExternalMSDS = [http://msds.chem.ox.ac.uk/PO/potassium_t-butoxide.html Oxford MSDS]
EUClass = Harmful (Xn), Corrosive (C)
FlashPt=
Autoignition=

Potassium "tert"-butoxide is a white solid with the chemical formula C4H9OK. It is a strong base, sometimes used in Schlosser's base.

Potassium "tert"-butoxide is commercially available. It may be prepared by refluxing dry "tert"-butanol with potassium metal. [OrgSynth | author = William S. Johnson and William P. Schneider | title = β-Carbethoxy-γ,γ-diphenylvinylacetic acid | collvol = 4 | collvolpages = 132 | prep = cv4p0132 | year = 1963]

The "tert"-butoxide species is itself useful as a strong, non-nucleophilic base in organic chemistry. It is able to abstract acidic protons from the substrate molecule readily, but its steric bulk inhibits the group from participating in nucleophilic addition, such as in a Williamson ether synthesis or an SN2 reaction.

References


Wikimedia Foundation. 2010.

Игры ⚽ Поможем написать реферат

Look at other dictionaries:

  • tert-Butanol — tert Butanol …   Wikipedia

  • Tert-Butanol — Chembox new Name = tert Butanol Reference = [ Merck Index , 11th Edition, 1542] ImageFileL1 = Tert butanol 2D skeletal.png ImageSizeL1 = 120px ImageNameL1 = tert Butanol ImageFileR1 = Tert butanol 3D balls.png ImageSizeR1 = 120px ImageNameR1 = t… …   Wikipedia

  • Kalium-tert-butanolat — Strukturformel Allgemeines Name Kalium tert butanolat Andere Namen …   Deutsch Wikipedia

  • Persistent carbene — A stable carbene: isolated 1,3 dimesitylimidazol 2 ylidene in a Schlenk flask (stir bar also present). A persistent carbene (also known as stable carbene or Arduengo carbene) is a type of carbene demonstrating particular stability. The best known …   Wikipedia

  • Superbase — In chemistry, a superbase is an extremely strong base. There is no commonly accepted definition for what qualifies as a superbase, but most chemists would accept sodium hydroxide as a benchmark base just as sulfuric acid is a benchmark acid (see… …   Wikipedia

  • Danishefsky Taxol total synthesis — overview from raw material perspective The Danishefsky Taxol total synthesis in organic chemistry is an important third Taxol synthesis published by the group of Samuel Danishefsky in 1996 [1] two years after the first two efforts …   Wikipedia

  • Hydromorphone — Systematic (IUPAC) name …   Wikipedia

  • Non-nucleophilic base — Acids and Bases Acid dissociation constant Acid base extraction Acid–base reaction Acid–base titration Dissociation constant Acidity function Buffer so …   Wikipedia

  • Oppenauer oxidation — Oppenauer oxidation, named after Rupert Viktor Oppenauer,[1] is a gentle method for selectively oxidizing secondary alcohols to ketones. The reaction is the opposite of Meerwein Ponndorf Verley reduction. The alcohol is oxidized with aluminium… …   Wikipedia

  • Holton Taxol total synthesis — The Holton Taxol total synthesis, published by Robert A. Holton and his group at Florida State University in 1994 was the first total synthesis of Taxol (generic name: paclitaxel) [ First total synthesis of taxol 1. Functionalization of the B… …   Wikipedia

Share the article and excerpts

Direct link
… Do a right-click on the link above
and select “Copy Link”