Lymphocytosis


Lymphocytosis

DiseaseDisorder infobox
Name = Lymphocytosis
ICD10 = ICD10|D|72|8|d|70
ICD9 = ICD9|288.8


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DiseasesDB = 7678
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MeshID = D008218

Lymphocytosis is an increase in the number or proportion of lymphocytes in the blood, usually detected when a complete blood count is routinely obtained. Lymphocytes normally represent 20 to 40% of circulating white blood cells. The absolute lymphocyte count (ALC) can be directly measured by flow cytometry, or calculated by multiplying the total white blood cell (WBC) count by the percentage of lymphocytes found in the differential count [ For example, if the total WBC count is 30,000, and the %lymphocytes is 30, the absolute lymphocyte count is 9,000 per microliter.] . In absolute lymphocytosis, the total lymphocyte count is elevated above the population reference range (normal). In adults, absolute lymphocytosis is present when the absolute lymphocyte count is greater than 4000 per microliter, in older children greater than 7000 per microliter and in infants greater than 9000 per microliter [ Miale, John B. Laboratory Medicine: hematology. 5th. St. Louis: C.V. Mosby, 1977.] . Relative lymphocytosis occurs when there is a higher proportion (greater than 40%) of lymphocytes among the white blood cells, however, absolute lymphocyte count (ALC) is normal (less than 4000 per microliter. Relative lymphocytosis is normal in children under age 2.

ymptoms

Lymphocytosis ia a feature of infection, particularly in children. In the elderly, lymphoproliferative disorders, including chronic lymphocytic leukaemia and lymphomas, often present with lymphadenopathy and a lymphocytosis. The symptoms of the underlying disease.........
Fever, general malaise, sore throat, lymphadenopathy, and atypical lymphocytes in the blood.

Causes

Causes of absolute lymphocytosis include:
* acute viral infections, such as infectious mononucleosis (glandular fever), Epstein-Barr virus infection, and hepatitis
* other acute infections such as pertussis
* some protozoal infections, such as toxoplasmosis and American trypanosomiasis (Chagas disease)
* chronic intracellular bacterial infections such as tuberculosis or brucellosis
* Acute Lymphoblastic Leukemia

Causes of relative lymphocytosis include: age less than 2 years; acute viral infections; connective tissue diseases, thyrotoxicosis, Addison's disease, and splenomegaly with splenic sequestration of granulocytes.

References

External links

* [http://pathmicro.med.sc.edu/ghaffar/bord-hemo.htm Illustration]


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Look at other dictionaries:

  • Lymphocytosis — vgl. Lymphozytose …   Das Wörterbuch medizinischer Fachausdrücke

  • lymphocytosis — [lim΄fō sī tō′sis] n. [ModL: see LYMPHOCYTE + OSIS] a condition characterized by an increase in the number of lymphocytes in the blood, as in acute or chronic infection lymphocytotic [lim΄fō sītät′ik] adj …   English World dictionary

  • Lymphocytosis — Too many lymphocytes, a finding that may be a marker for infection or disease. * * * A form of actual or relative leukocytosis in which there is an increase in the number of lymphocytes. SYN: lymphocythemia, lymphocytic leukocytosis. * * *… …   Medical dictionary

  • lymphocytosis — n. an increase in the number of lymphocytes in the blood. Lymphocytosis may occur in a wide variety of diseases, including chronic lymphocytic leukaemia and infections due to viruses …   The new mediacal dictionary

  • lymphocytosis — noun Etymology: New Latin, from International Scientific Vocabulary lymphocyte Date: 1896 an increase in the number of lymphocytes in the blood usually associated with chronic infections or inflammations …   New Collegiate Dictionary

  • lymphocytosis — lymphocytotic /lim foh suy tot ik/, adj. /lim feuh suy toh sis/, n. Pathol. an abnormal increase in the number of lymphocytes in the blood. [1895 1900; LYMPHOCYTE + OSIS] * * * …   Universalium

  • lymphocytosis — noun An increase in the number or proportion of lymphocytes in the blood …   Wiktionary

  • lymphocytosis — n. abnormally large number of lymphocytes in the blood (Medicine) …   English contemporary dictionary

  • lymphocytosis — lym·pho·cy·to·sis …   English syllables

  • lymphocytosis — lym•pho•cy•to•sis [[t]ˌlɪm fə saɪˈtoʊ sɪs[/t]] n. pat an abnormal increase in the number of lymphocytes in the blood • Etymology: 1895–1900 lym pho•cy•tot′ic ˈtɒt ɪk adj …   From formal English to slang