Phylloquinone


Phylloquinone
Phylloquinone
Identifiers
CAS number 84-80-0
PubChem 4812
ChemSpider 4447652
UNII A034SE7857
DrugBank DB01022
ChEBI CHEBI:18067
ChEMBL CHEMBL1550 YesY
Jmol-3D images Image 1
Properties
Molecular formula C31H46O2
Molar mass 450.7 g mol−1
Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
Infobox references

Phylloquinone is a polycyclic aromatic ketone, based on 2-methyl-1,4-naphthoquinone, with a 3-phytyl substituent.

It is a fat-soluble vitamin that is stable to air and moisture but decomposes in sunlight. It is found naturally in a wide variety of green plants.

Contents

Terminology

It is often called vitamin K1[1] or phytonadione. Sometimes a distinction is made with phylloquinone considered natural and phytonadione considered synthetic.[2]

A stereoisomer of phylloquinone is called vitamin k1 (note the difference in capitalization).

Mechanism

Its best known mechanism of action is as a cofactor in the formation of coagulation factors II (prothrombin), VII, IX and X by the liver. Vitamin K1 is commonly used to treat warfarin toxicity, and an antidote for coumatetralyl. It is also required for the formation of anticoagulant factors protein C and S. Vitamin K is also required for bone protein formation.

Phylloquinone is an electron acceptor in the electron transport chain of chloroplasts.

See also

References


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Look at other dictionaries:

  • Phylloquinone — Structure de la phylloquinone Général Nom IUPAC 2 méthyl 3 [(2E) 3,7,11,15 tétramethylhexadéc …   Wikipédia en Français

  • phylloquinone — ● phylloquinone nom féminin Naphtoquinone C31H46O2, qui est la vitamine K1 antihémorragique …   Encyclopédie Universelle

  • phylloquinone — filochinonas statusas T sritis chemija apibrėžtis 2 metil 1,4 naftochinono darinys su izoprenoidine grandine trečiojoje padėtyje. atitikmenys: angl. phylloquinone; vitamin K rus. витамин K; филлохинон ryšiai: sinonimas – vitaminas K …   Chemijos terminų aiškinamasis žodynas

  • phylloquinone — /fil oh kwi nohn , kwin ohn/, n. Biochem. See vitamin K1. [1935 40; PHYLLO + QUINONE] * * * …   Universalium

  • phylloquinone — noun a) A polycyclic aromatic ketone, based on 2 methyl 1,4 naphthoquinone. b) Vitamin K Syn: phytonadione, phytomenadione See Also: naphthoquinone …   Wiktionary

  • phylloquinone — Isolated from alfalfa; also prepared synthetically; major form of vitamin K found in plants. SYN: phytomenadione, phytonadione, vitamin K1, vitamin K1(20). p. reductase SYN: NADPH dehydrogenase (quinone). * * * phyl·lo·qui·none .fil ō kwin ōn,… …   Medical dictionary

  • phylloquinone — n. vitamin K 1 …   English contemporary dictionary

  • phylloquinone — [ˌfɪlə(ʊ) kwɪnəʊn] noun Biochemistry vitamin K1, a compound found in cabbage, spinach, and other leafy green vegetables, and essential for the blood clotting process …   English new terms dictionary

  • phylloquinone — phyl·lo·quinone …   English syllables

  • phylloquinone — phyl•lo•qui•none [[t]ˌfɪl oʊ kwɪˈnoʊn, ˈkwɪn oʊn[/t]] n. biochem. nut vitamin K1. • Etymology: 1935–40 …   From formal English to slang


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