- Brodmann area 15
Brodmann's Area 15 is one of
Brodmann's subdivisions of the cerebral cortexin the brain.
Area 15 is located in the part of the insula nearest the
temporal lobeand part of the anteriortemporal lobe facing the insula.Brain Info [http://braininfo.rprc.washington.edu/Scripts/ancilcentraldirectory.aspx?ID=1054769984 Brodmann Area 15] visited 1/22/2007] It is buried in the Sylvian Fissure and thus not visible on the surface of the brain without dissection.
Area 15, like all Brodmann's areas is defined on the basis of
cytoarchitectureof the region of cortex. The cortex in area 15 is thinner than in the rest of the insula and temporal lobe. The molecular layer (I) is unusually wide; the external granular layer (II) and the external pyramidal layer (III) are less dense, and the internal granular layer (IV) is totally absent, so that the medium-sized pyramidal cells of layer III and the internal pyramidal layer (V) merge with a few isolated granular cells scattered at their boundary. The multiform layer (VI) divides into a more densely cellular outer sublayer (VIa) and a less dense inner sublayer (VIb). As in Brodmann area 14, the sublayer VIb merges with the adjacent claustrum. The cells in all of layer VI form tangential rows similar to the formation seen in area 10 and area 11.
Existence in Humans
Brodmann Area 15 is one of the areas that was not found in humans; however, at least once research group has found an area in approximately the correct anatomical location with similar functions.Fischer, et Al. " [http://dx.doi.org/10.1016/S0304-3940(98)00503-5 Brain correlates of an unexpected panic attack: a human positron emission tomographic study] ". "Neuroscience Letters" 251(2):137-140 (1998)]
Area 15 is the cortical target of information coming through
Hering's nerves. [Tubbs et Al. " [http://dx.doi.org/10.1159/000066214 Cortical Representation of Hering's Nerve: A Possible Anatomical Pathway for Seizure Cessation following Electrical Stimulation] ." "Pediatric Neurosurgery" 24(5) (2002)] It therefore receives input from the carotidsinus relaying blood pressureand blood chemistryinformation to the brain. [whonamedit [http://www.whonamedit.com/synd.cfm/3187.html Hering's nerves] visited 1/22/2007] The nerve gets this information from baroreceptors and chemoreceptors located in the carotid artery. This region has been shown to be active during panic attacks.
List of regions in the human brain
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