Chief cell

Chief cell

In general, a chief cell (or a "zymogenic cell") is a cell which releases a precursor enzyme. There are two types of chief cells which are most commonly referenced:

  • A gastric chief cell (or "peptic cell") is a cell in the stomach that releases pepsinogen and rennin. Usually when the term "chief cell" or "zymogenic cell" is used without qualification, this is the type meant. This type of cell also secretes gastric lipase enzymes, which help digest triglycerides into free fatty acids and di- and mono-glycerides.
  • The parathyroid chief cell is the primary cell of the parathyroid gland. It produces and secretes parathyroid hormone.

References


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  • chief cell — chēf n 1) one of the cells that line the lumen of the fundic glands of the stomach: a) a small cell with granular cytoplasm that secretes pepsin b) a larger cell with hyaline cytoplasm and a mucoid secretion compare PARIETAL CELL 2) one of the se …   Medical dictionary

  • chief cell — noun 1. : one of the cells that line the lumen of the fundic glands of the stomach: a. : a small cell with granular cytoplasm that secretes pepsin b. : a larger cell with hyaline cytoplasm and a mucoid secretion compare parietal cell 2. : one of… …   Useful english dictionary

  • Gastric chief cell — Chief cell H E stain of fundic gland polyp showing shortening of the gastric pits with cystic dilatation …   Wikipedia

  • chief cell adenoma — adenoma of the parathyroid gland composed of solid masses of small chief cells similar to those seen in the normal gland …   Medical dictionary

  • Parathyroid chief cell — Parathyroid chief cells are cells in the parathyroid glands which produce parathyroid hormone. The end result of increased secretion by the chief cells of a parathyroid gland is an increase in the serum level of Calcium. Parathyroid chief cells… …   Wikipedia

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